Name: 2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE
SKU: 902-04-5

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Basic Information

CAS No.:

902-04-5

Name:

2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE

Molecular Structure:

Formula:

C10H14 N5 O7 P

Molecular Weight:

347.224

Synonyms:

Guanosine,2'-deoxy-, 5'-(dihydrogen phosphate) (8CI); Guanosine, 2'-deoxy-, 5'-phosphate(6CI); Guanosine, 2'-deoxy-, phosphate (7CI); 2'-Deoxy-5'-GMP;2'-Deoxy-5'-guanylic acid; 2'-Deoxy-GMP; 2'-Deoxyguanosine 5'-monophosphate;2'-Deoxyguanosine 5'-phosphate; 2'-Deoxyguanylic acid; 2'-dGMP; Deoxy-GMP;Deoxyguanosine 5'-monophosphate; Deoxyguanosine 5'-phosphate; NSC 82626; dGMP

Density:

2.32g/cm³

Melting Point:

180-182oC

Boiling Point:

844.2°Cat760mmHg

Flash Point:

464.4°C

Safety:

WGK Germany

PSA:

195.62000

LogP:

-0.95930

Synthetic route

: 961-07-9
2'-Deoxyguanosine

: 902-04-5
2'-deoxyguanosine 5'-monophosphate

Conditions

Conditions	Yield
Stage #1: 2'-Deoxyguanosine With trichlorophosphate at 20℃; for 0.15h; Flow reactor; Green chemistry; Stage #2: With water at 20℃; Temperature; Flow reactor; Green chemistry; chemoselective reaction;	74%
With high Km 5'-nucleotidase; 5'-inosine monophosphate; ATP In various solvents at 37℃; pH=6.5; Enzyme kinetics; Further Variations:; Reagents; Solvents;
With Tris-HCl buffer; recombinant human mitochondrial deoxyguanosine kinase; ATP In water; dimethyl sulfoxide at 37℃; pH=7.6; Enzyme kinetics;
With recombinant deoxyribonucleoside kinase AtdNK from Arabidopsis thaliana (ecotype Columbia); ATP In aq. buffer Kinetics; Concentration; Reagent/catalyst; Enzymatic reaction;
With drosophila melanogaster deoxyribonucleoside kinase; ATP; magnesium chloride In aq. buffer at 37℃; for 24h; pH=8; Enzymatic reaction;

: 701-64-4
phosphoric acid monophenyl ester

: 961-07-9
2'-Deoxyguanosine

: 902-04-5
2'-deoxyguanosine 5'-monophosphate

Conditions

Conditions	Yield
mit Hilfe von Malzenzym;

: O3'-acetyl-O5'-benzyloxyphosphinoyl-2'-deoxy-guanosine

: 902-04-5
2'-deoxyguanosine 5'-monophosphate

Conditions

Conditions	Yield
ueber mehrere Stufen;

: C71H97N27O50P8

A: 1032-65-1
cytidine 5'-(dihydrogen phosphate)

B: 4603-58-1
Thymidine

C: Phosphoric acid (2R,3S,5R)-5-(5-amino-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester 2,3,5-trihydroxy-pentyl ester

D: 902-04-5
2'-deoxyguanosine 5'-monophosphate

Conditions

Conditions	Yield
With alkaline phosphatase; snake venom phosphodiesterase Further byproducts given;

...Expand

: 4-Methoxy-benzoic acid (2R,3S,5R)-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester

: 902-04-5
2'-deoxyguanosine 5'-monophosphate

Conditions

Conditions	Yield
With pyridine; ammonium hydroxide at 50℃; for 12h;

: deoxyguanosine 5'-monophosphate 2-methylimidazolide

: 7365-45-9
N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid

A: 902-04-5
2'-deoxyguanosine 5'-monophosphate

B: 2-[4-(2-{[(2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphoryloxy}-ethyl)-piperazin-1-yl]-ethanesulfonic acid

C: C20H24N10O13P2(2-)

D: C30H35N15O19P3(3-)

Conditions

Conditions	Yield
With sodium chloride; magnesium chloride; polycytidylate In water at 23℃; for 480h; pH=7.85; Kinetics; Product distribution; Further Variations:; Reagents; Condensation; dimerization; oligomerization; hydrolysis;

...Expand