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CAS No.: | 902-04-5 | ||
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Name: | 2'-DEOXYGUANOSINE 5'-MONOPHOSPHATE | ||
Article Data: | 21 | ||
Molecular Structure: | |||
Formula: | C10H14 N5 O7 P | ||
Molecular Weight: | 347.224 | ||
Synonyms: | Guanosine,2'-deoxy-, 5'-(dihydrogen phosphate) (8CI); Guanosine, 2'-deoxy-, 5'-phosphate(6CI); Guanosine, 2'-deoxy-, phosphate (7CI); 2'-Deoxy-5'-GMP;2'-Deoxy-5'-guanylic acid; 2'-Deoxy-GMP; 2'-Deoxyguanosine 5'-monophosphate;2'-Deoxyguanosine 5'-phosphate; 2'-Deoxyguanylic acid; 2'-dGMP; Deoxy-GMP;Deoxyguanosine 5'-monophosphate; Deoxyguanosine 5'-phosphate; NSC 82626; dGMP | ||
Density: | 2.32g/cm3 | ||
Melting Point: | 180-182oC | ||
Boiling Point: | 844.2°Cat760mmHg | ||
Flash Point: | 464.4°C | ||
Safety: |
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PSA: | 195.62000 | ||
LogP: | -0.95930 |
Conditions | Yield |
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Stage #1: 2'-Deoxyguanosine With trichlorophosphate at 20℃; for 0.15h; Flow reactor; Green chemistry; Stage #2: With water at 20℃; Temperature; Flow reactor; Green chemistry; chemoselective reaction; | 74% |
With high Km 5'-nucleotidase; 5'-inosine monophosphate; ATP In various solvents at 37℃; pH=6.5; Enzyme kinetics; Further Variations:; Reagents; Solvents; | |
With Tris-HCl buffer; recombinant human mitochondrial deoxyguanosine kinase; ATP In water; dimethyl sulfoxide at 37℃; pH=7.6; Enzyme kinetics; | |
With recombinant deoxyribonucleoside kinase AtdNK from Arabidopsis thaliana (ecotype Columbia); ATP In aq. buffer Kinetics; Concentration; Reagent/catalyst; Enzymatic reaction; | |
With drosophila melanogaster deoxyribonucleoside kinase; ATP; magnesium chloride In aq. buffer at 37℃; for 24h; pH=8; Enzymatic reaction; |
phosphoric acid monophenyl ester
2'-Deoxyguanosine
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
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mit Hilfe von Malzenzym; |
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
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ueber mehrere Stufen; |
A
cytidine 5'-(dihydrogen phosphate)
B
Thymidine
D
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
---|---|
With alkaline phosphatase; snake venom phosphodiesterase Further byproducts given; |
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
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With pyridine; ammonium hydroxide at 50℃; for 12h; |
N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid
A
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
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With sodium chloride; magnesium chloride; polycytidylate In water at 23℃; for 480h; pH=7.85; Kinetics; Product distribution; Further Variations:; Reagents; Condensation; dimerization; oligomerization; hydrolysis; |
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
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With ammonium hydroxide In water at 65℃; for 6h; Hydrolysis; |
Conditions | Yield |
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With water; MutT Hydrolysis; |
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
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With MutT pyrophosphohydrolase; magnesium chloride In various solvent(s) at 23℃; pH=7.5; Enzyme kinetics; |
2'-deoxyguanosine 5'-monophosphate
Conditions | Yield |
---|---|
Multistep reaction; |