10292-60-1Relevant articles and documents
Novel photohydration of non-conjugated aryl/olefin bichromophores within cyclodextrin cavities
Benali,Jimenez,Miranda,Tormos
, p. 2328 - 2329 (2001)
Cyclodextrin media are used to achieve photochemical water addition to isolated, acyclic double bonds via intramolecular interaction with excited arenes.
Isomerization of 2-(2-propenoxy)phenyllithium: Tandem anionic cyclization-γ-elimination
Bailey, William F.,Punzalan, Eric R.
, p. 5435 - 5436 (1996)
2-(2-Propenoxy)phenyllithium (1), which may be prepared from the corresponding iodide by low-temperature lithium-iodine exchange, rearranges on warming in the presence of TMEDA via 5-exo cyclization to (2,3-dihydrobenzofuranyl)methyllithium (2) followed by γ-elimination to give variable amounts of the lithium salt of 2-(cyclopropyl)phenol (3).
Diastereo- and enantioselective carbolithiation of allyl o-lithioaryl ethers. New chiral cyclopropane derivatives
Barluenga, Jose,Fananas, Francisco J.,Sanz, Roberto,Marcos, Cesar
, p. 2225 - 2228 (2002)
(matrix presented) Different allyl 2-lithioaryl ethers undergo a tandem carbolithiation/γ-elimination in Et2OH-MEDA affording o-cyclopropyl phenol or naphthol derivatives in a diastereoselective manner. The use of (-)-sparteine as a chiral liga
5H-PYRROLO[3,4-£>]PYRAZIN-7-AMINE DERIVATIVES INHIBITORS OF BETA-SECRETASE
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, (2011/02/24)
The present invention relates to novel compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Downs syndrome, β- amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI ("mild cognitive impairment"), Alzheimer Disease, memory loss, attention deficit symptoms associated with Alzheimer disease, neurodegeneration associated with diseases such as Alzheimer disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.
NEW COMPOUNDS 574
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Page/Page column 27, (2010/06/13)
The present invention relates to novel compounds of formula (I) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Downs syndrome,