105278-81-7Relevant articles and documents
REACTIONS OF 4-CHLORO-1-NITROBENZENE WITH (3-CHLORO-4-METHOXYPHENYL)ACETONITRILE AND (3,4-DIMETHOXYPHENYL)ACETONITRILE; SYNTHESIS OF 8-CHLORO-1-METHYL (AND METHYLTHIOMETHYL)-6-(3,4-DISUBSTITUTED PHENYL)-4H-s-TRIAZOLO-1,4-BENZODIAZEPINES
Vejdelek, Zdenek,Holubek, Jiri,Budesinsky, Milos,Ryska, Miroslav,Svatek, Emil,Protiva, Miroslav
, p. 361 - 372 (2007/10/02)
Reactions of 4-chloro-1-nitrobenzene with (3-chloro-4-methoxyphenyl)acetonitrile and (3,4-dimethoxyphenyl)acetonitrile in methanolic potassium hydroxide gave the corresponding 3-aryl-5-chloro-2,1-benzisoxazoles Ia and Ib in good yields; compounds Va, Vb, VI-VIII, and X were isolated as by-products and identified by means of spectra.Compounds Ia and Ib were transformed in five steps to the title componds XVab and XVIab which were found inactive in tests for central depressant and anticonvulsant activity.