114079-04-8Relevant articles and documents
Synthesis of Alkylphosphon(othio)ate Analogues of DNA
Roelen, H. C. P. F.,Elst, H. van den,Dreef, C. E.,Marel, G. A. van der,Boom, J. H. van
, p. 2357 - 2360 (2007/10/02)
Easily accessible bis(diisopropylamino)alkylphosphines (alkyl is methyl, n-butyl or n-octyl) are convenient reagents for the synthesis of DNA fragments having an alkylphosphonate or alkylphosphonothioate linkage at a predetermined site in solution and on
1,1-Bis-(4-methoxyphenyl)-1'-pyrenyl methyl (bmpm): A new fluorescent 5' protecting group for the purification of unmodified and modified oligonucleotides
Fourrey,Varenne,Blonski,Dousset,Shire
, p. 5157 - 5160 (2007/10/02)
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PHOSPHORAMIDITES AS SYNTHONS FOR POLYNUCLEOTIDE SYNTHESIS
Caruthers, Marvin H.,Brill, Wolfgang,Dellinger, Douglas J.
, p. 549 - 554 (2007/10/02)
Methods for the rapid synthesis of DNA and RNA are described.The procedures involve using nucleoside phosphoramidites as synthons and silica as a polymeric support.Additionally, a novel reaction involving nucleoside O-alkyl methylphosphonothioates is described.