13370-62-2 Usage
Description
[(4-BROMOPHENYL)AMINO]ACETIC ACID, also known as 4-Bromoanilinoacetic acid, is an organic compound characterized by the molecular formula C8H8BrNO2. It is a derivative of acetic acid, featuring a bromine atom attached to a benzene ring and an amine group. [(4-BROMOPHENYL)AMINO]ACETIC ACID is utilized in pharmaceutical research and development, and it holds potential for the synthesis of a variety of organic compounds. Its chemical properties render it a valuable building block for constructing more complex molecules, and it may also possess bioactive properties that warrant investigation for potential pharmaceutical applications.
Uses
Used in Pharmaceutical Research and Development:
[(4-BROMOPHENYL)AMINO]ACETIC ACID is used as a chemical intermediate for the synthesis of various organic compounds, particularly in the pharmaceutical industry. Its unique structure allows for the creation of more complex molecules that can be further explored for their therapeutic potential.
Used in Organic Synthesis:
In the field of organic chemistry, [(4-BROMOPHENYL)AMINO]ACETIC ACID is used as a building block for the development of new compounds. Its presence of a bromine atom and an amine group provides versatility in chemical reactions, facilitating the formation of a wide range of organic products.
Used in Bioactive Compound Exploration:
Given its potential bioactive properties, [(4-BROMOPHENYL)AMINO]ACETIC ACID is used in the study of biological activities. Researchers investigate its interactions with biological systems to understand its effects and possible applications in medicine.
Used in Drug Discovery:
In the drug discovery process, [(4-BROMOPHENYL)AMINO]ACETIC ACID may be employed as a starting material to identify new drug candidates. Its unique chemical structure could lead to the development of novel therapeutic agents with specific pharmacological actions.
Used in Chemical Education and Training:
[(4-BROMOPHENYL)AMINO]ACETIC ACID can also be utilized in educational settings, serving as a model compound for teaching organic chemistry concepts, particularly those related to functional group chemistry and the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 13370-62-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,7 and 0 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13370-62:
(7*1)+(6*3)+(5*3)+(4*7)+(3*0)+(2*6)+(1*2)=82
82 % 10 = 2
So 13370-62-2 is a valid CAS Registry Number.
13370-62-2Relevant articles and documents
Synthesis and evaluation of photo-activatable β-diarylsydnone-L-alanines for fluorogenic photo-click cyclization of peptides
Yao, Zhuojun,Wu, Xueting,Zhang, Xiaocui,Xiong, Qin,Jiang, Shichao,Yu, Zhipeng
, p. 6777 - 6781 (2019)
Herein, we design and synthesize a series of photoactivatable β-diarylsydnone-l-alanines (DASAs), which have excellent photo-reactivity with high fluorescence turn-on toward alkenes in a biocompatible environment. The environmental sensing properties of t
Discovery and evolution of 12N-substituted aloperine derivatives as anti-SARS-CoV-2 agents through targeting late entry stage
Wang, Kun,Wu, Jia-Jing,Xin–Zhang,Zeng, Qing-Xuan,Zhang, Na,Huang, Wei-Jin,Tang, Sheng,Wang, Yan-Xiang,Kong, Wei-Jia,Wang, You-Chun,Li, Ying-Hong,Song, Dan-Qing
, (2021/08/03)
So far, there is still no specific drug against COVID-19. Taking compound 1 with anti-EBOV activity as the lead, fifty-four 12N-substituted aloperine derivatives were synthesized and evaluated for the anti-SARS-CoV-2 activities using pseudotyped virus model. Among them, 8a exhibited the most potential effects against both pseudotyped and authentic SARS-CoV-2, as well as SARS-CoV and MERS-CoV, indicating a broad-spectrum anti-coronavirus profile. The mechanism study disclosed that 8a might block a late stage of viral entry, mainly via inhibiting host cathepsin B activity rather than directly targeting cathepsin B protein. Also, 8a could significantly reduce the release of multiple inflammatory cytokines in a time- and dose-dependent manner, such as IL-6, IL-1β, IL-8 and MCP-1, the major contributors to cytokine storm. Therefore, 8a is a promising agent with the advantages of broad-spectrum anti-coronavirus and anti-cytokine effects, thus worthy of further investigation.
Mechanosynthesis of sydnone-containing coordination complexes
Pétry, Nicolas,Vanderbeeken, Thibaut,Malher, Astrid,Bringer, Yoan,Retailleau, Pascal,Bantreil, Xavier,Lamaty, Frédéric
supporting information, p. 9495 - 9498 (2019/08/15)
N-Phenyl-4-(2-pyridinyl) sydnone was shown to act as a four-electron donor N,O-ligand in unprecedented coordination complexes featuring three different metallic centers (Co, Cu, and Zn). Starting with various anilines, the use of a ball-mill efficiently enabled the synthesis of N-arylglycines, subsequent nitrosylation and cyclization into sydnones, and further metalation.