16703-52-9Relevant articles and documents
Donatsch et al.
, p. 1185 (1970)
SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE
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Paragraph 000667, (2019/06/05)
The present invention provides novel heteroaryl compounds, pharmaceutical acceptable salts and formulations thereof. They are useful in preventing, managing, treating or lessening the severity of a protein kinase-mediated disease. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of protein kinase-mediated disease.
Synthesis of 2,3-allenylamides utilizing [1,2]-phospha-Brook rearrangement and their application to gold-catalyzed cycloisomerization providing 2-aminofuran derivatives
Kondoh, Azusa,Ishikawa, Sho,Aoki, Takuma,Terada, Masahiro
supporting information, p. 12513 - 12516 (2016/10/24)
An efficient synthetic method for 2,3-allenylamides having an oxygen functionality at the 2-position, which are difficult to access by conventional methods, was newly developed by utilizing the [1,2]-phospha-Brook rearrangement under Br?nsted base catalysis. Further manipulation of the 2,3-allenylamides via gold-catalyzed cycloisomerization enables the formation of 2-aminofuran derivatives.