101080-02-8 Usage
Functional groups
Chloromethyl group, methoxy group, nitro group
Structure
Chloromethyl and methoxy groups attached to a benzene ring, with a nitro group at position 2
Applications
a. Synthesis of pharmaceutical and agrochemical intermediates
b. Organic synthesis and chemical research as a building block for creating more complex molecules
c. Potential applications in the pharmaceutical industry
d. Development of new materials and chemical processes
Chemical properties
a. Reactivity with nucleophiles due to the presence of the chloromethyl group
b. Reactivity with electrophiles due to the presence of the methoxy group
c. Reactivity with reducing agents due to the presence of the nitro group
Appearance
Likely a solid or crystalline substance (not specified in the material)
Solubility
Likely soluble in organic solvents such as dichloromethane, acetone, or ethanol (not specified in the material)
Stability
Stable under normal conditions, but may decompose upon exposure to heat or light (not specified in the material)
Check Digit Verification of cas no
The CAS Registry Mumber 101080-02-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,0,8 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 101080-02:
(8*1)+(7*0)+(6*1)+(5*0)+(4*8)+(3*0)+(2*0)+(1*2)=48
48 % 10 = 8
So 101080-02-8 is a valid CAS Registry Number.
101080-02-8Relevant articles and documents
Vicarious Nucleophilic Chloromethylation of Nitroaromatics
Khutorianskyi, Viktor V.,Klepetá?ová, Blanka,Beier
supporting information, p. 5443 - 5446 (2019/07/03)
Nitroaromatics substituted with electron-acceptor or electron-donor groups undergo vicarious nucleophilic substitution with the lithium salt of dichloromethane to provide chloromethyl-substituted nitroaromatics in good to high yields. The methodology represents a new strategy for the synthesis of benzyl chlorides.
TETRAHYDRO-PYRIDOAZEPIN-8-ONES AND RELATED COMPOUNDS FOR THE TREATMENT OF SCHIZOPHRENIA
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Page/Page column 68, (2010/11/24)
Compounds of formula 1 are disclosed, wherein G, D, A, Q, Y, Z, and R1 through R10 are defined in the specification. Also provided are descriptions of processes for preparing compounds of formula 1, intermediates used in making the same, and pharmaceutical compositions containing such compounds and their use in the treatment of central nervous system disorders and other disorders.
