10154-76-4Relevant articles and documents
Water-Promoted Michael Addition Reaction of Sulfonyl Hydrazides and α, β-Unsaturated Propionic Acids to 3-Sulfone Propionic Acids
Gao, Lingfeng,Liu, Yifan,Qi, Zhiyuan,Sun, Xu,Zhang, Qilong,Zhao, Panfeng,Zheng, Gengxiu
supporting information, (2022/05/02)
A water-promoted synthesis methodology for constructing 3-sulfone propionic acids from sulfonyl hydrazides and α, β-unsaturated propionic acids with excellent yields were reported. The green synthesis methodology was promoted by water without any catalyst, ligand and organic solvent. The D2O control experiment sufficiently proved that the 2-hydrogen atom of 3-sulfone propionic acid come from water. Moreover, the 3-sulfone propionic acid derivates could be directly purified by crystallization without column chromatography.
A structure-taste study of arylsulfonyl(cyclo)alkanecarboxylic acids
Lysiak, Violetta,Ratajczak, Aleksander,Mencel, Agnieszka,Jarzembek, Krystyna,Polanski, Jaroslaw
, p. 671 - 675 (2007/10/03)
A number of sweeteners contain a sulfonyl group. In our current search for new glucophores several new compounds containing such group were obtained. A series of novel 1-phenylsulfonylcyklohexanecarboxylic acids and 2-arylsulfonylalkanecarboxylic acids was obtained and evaluated for their sweet taste quality. It has been found that methyl substituents are of the key importance for the activity of these compounds.
Lithium 3-lithio-3-tosylpropanoate: A useful α-tosylated homoenolate anion
Bonete,Najera
, p. 4065 - 4068 (2007/10/02)
Lithium 3-lithio-3-tosylpropanoate prepared by dilithiation of 3-tosylpropanoic acid with n-butyllithium at -78°C, reacts with different electrophiles yielding the expected 3-functionalized tosylated propanoic acids. When carbonyl compounds are used as electrophiles the corresponding α,β-butenolides are prepared directly.
