1016-82-6

Usage

General Description

The chemical compound "(p-Chlorophenyl)(phenyl) sulfoxide" is an organic compound that is composed of a chlorophenyl group and a phenyl group attached to a sulfoxide functional group. It is a white crystalline solid that is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. (p-Chlorophenyl)(phenyl) sulfoxide has potential applications in the field of organic chemistry, particularly in the production of sulfoxides and related compounds. It is also known to exhibit mild oxidizing properties, making it useful in certain chemical reactions. Additionally, it is important to handle (p-Chlorophenyl)(phenyl) sulfoxide with care as it can be irritating to the skin and eyes, and should be stored and disposed of properly to minimize environmental impact.

InChI:InChI=1/C12H9ClOS/c13-10-6-8-12(9-7-10)15(14)11-4-2-1-3-5-11/h1-9H

Upstream product

• 13343-26-5 phenyl p-chlorophenyl sulfide 
• 75945-35-6 (±)-(4-chlorophenyl)(imino)(phenyl)-λ⁶-sulfanone 
• 873-55-2 sodium benzenesulfonate 
• 108-90-7 chlorobenzene 
• 7601-90-3 perchloric acid 
• 64-17-5 ethanol 
• 7722-84-1 dihydrogen peroxide 
• 71-43-2 benzene 
• 36744-94-2 C₁₂H₁₀ClNS 
• 56075-36-6 1-(4-chlorophenyl)-2-(methylsulfonyl)diazene 
• 108-98-5 thiophenol 
• 98-80-6 phenylboronic acid 
• 1679-18-1 4-Chlorophenylboronic acid 
• 106-54-7 p-Chlorothiophenol 

Downstream Products

• 945-51-7 1,1'-sulfinylbisbenzene 
• 3085-42-5 bis(4-chlorophenyl)sulfoxide 
• 2051-62-9 4'-biphenyl chloride 

Relevant academic research and scientific papers

Aqueous sodium hypochlorite mediated chemoselective oxidation of chalcogenides to monoxides and dioxides by microwave exposure

A solvent-free, rapid, and highly selective oxidation of sulfides, selenides, and tellurides (chalcogenides) to the corresponding monoxides (sulfoxides, selenoxides, and telluroxides) or the corresponding dioxides (sulfones, selenones, and tellurones) has been developed using aqueous sodium hypochlorite on solid supports by exposure to microwave. Chemoselectivity and quantitative yields have been attained in most cases.

Mechanism of Picolinic-acid-catalysed Chromium(VI) Oxidation of Alkyl Aryl and Diphenyl Sulphides

The kinetics of picolinic acid (PA)-catalysed Cr(VI) oxidation of organic sulphur compounds have been studied with several alkyl aryl sulphides and diphenyl sulphides in acetic acid-water mixtures.The PA-catalysed oxidation follows third-order kinetics, f

Mechanism of (salen)manganese(III)-catalyzed oxidation of aryl phenyl sulfides with sodium hypochlorite

The oxidation of 4-substituted phenyl phenyl sulfides was carried out with several oxo(salen)manganese( V) complexes in MeCN/H2O9 : 1. The kinetic data show that the reaction is first-order each in the oxidant and sulfide. Electron-attracting s

Nickel(II)/N-Heterocyclic Carbene Catalyzed Desulfinylative Arylation by C?S Cleavage of Aryl Sulfoxides with Phenylboronic Acids

Suzuki-Miyaura coupling of haloarenes is the most widely used protocol for the synthesis of biphenyls. Organosulfur compounds are promising electrophiles since they are abundant in nature and versatile in organic synthesis. We report here the desulfinylative Suzuki-Miyaura coupling of aryl sulfoxides with phenylboronic acids using bench-stable nickel/5-(2,4,6-triisopropylphenyl)imidazolylidene[1,5-a]pyridines as the catalyst. The ligands are readily prepared from common commercial chemicals. The method is applicable to both symmetric and unsymmetric aryl sulfoxides, and a range of biphenyls bearing various functional groups were obtained in up to 94% yield. (Figure presented.).

One-pot synthesis of aryl sulfoxides and sulfonium salts from sulfinic acid as a novel sulfurizing agent

Sodium sulfinate reacts electrophilically with aromatics in trifluoromethanesulfonic acid to give the corresponding aryl sulfoxides and sulfonium salts.

Supported vanadium Schiff bases complex on nano silica: a heterogeneous catalyst for the selective oxidation of sulfides and alcohols

Abstract: A vanadium Schiff base complex on nano silica was prepared by reaction of nano silica NH2-functionalized, 2,4-dihydroxy benzaldehyde and VO(acac)2. The VSBC@NS was used as an efficient and reusable heterogeneous catalyst fo

A selective and convenient oxidation of sulfides to sulfoxides with trichloroisocyanuric acid

Sulfides are readily oxidized to sulfoxides by a solution of pyridine, water, and trichloroisocyanuric acid in acetonitrile and methylene chloride.

TELLURIUM DIOXIDE CATALYZED SELECTIVE OXIDATION OF SULFIDES TO SULFOXIDES WITH HYDROGEN PEROXIDE

TeO2-H2O2 system was found to be an efficient selective reagent for the oxidation of sulfides to sulfoxides in the presence of other common functional groups.Over-oxidation of sulfoxides to sulfones was not observed.

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.

Room temperature nickel-catalyzed cross-coupling of aryl-boronic acids with thiophenols: Synthesis of diarylsulfides

A NiCl2/2,2′-bipyridine-catalyzed cross-coupling of thiophenols with arylboronic acids has been developed for the synthesis of symmetric and unsymmetric diarylsulfides at room temperature and in air. This methodology is reliable and offers a mild and easy to operate process for the synthesis of arylthioethers, which are essential compounds with applications in the pharmaceutical and agricultural industries. This method avoids the use of expensive transition metals, such as Pd, Ir or Rh, sophisticated ligands and elevated temperatures. It also has a wide substrate scope (55 examples) and provides products in good to excellent yields (72-93%).