1016-82-6

Basic information

• Product Name: (p-Chlorophenyl)(phenyl) sulfoxide
• Synonyms: (p-Chlorophenyl)(phenyl) sulfoxide;p-Chlorophenylphenyl sulfoxide;1-chloro-4-[(R)-phenylsulfinyl]benzene
• CAS NO: 1016-82-6
• Molecular Formula: C₁₂H₉ClOS
• Molecular Weight: 236.7173
• Mol File: 1016-82-6.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 382.7°Cat760mmHg
• Flash Point: 185.3°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 1.02E-05mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: (p-Chlorophenyl)(phenyl) sulfoxide(CAS DataBase Reference)
• NIST Chemistry Reference: (p-Chlorophenyl)(phenyl) sulfoxide(1016-82-6)
• EPA Substance Registry System: (p-Chlorophenyl)(phenyl) sulfoxide(1016-82-6)

Safety Data

• Hazardous Substances Data: 1016-82-6(Hazardous Substances Data)

Usage

General Description

The chemical compound "(p-Chlorophenyl)(phenyl) sulfoxide" is an organic compound that is composed of a chlorophenyl group and a phenyl group attached to a sulfoxide functional group. It is a white crystalline solid that is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. (p-Chlorophenyl)(phenyl) sulfoxide has potential applications in the field of organic chemistry, particularly in the production of sulfoxides and related compounds. It is also known to exhibit mild oxidizing properties, making it useful in certain chemical reactions. Additionally, it is important to handle this compound with care as it can be irritating to the skin and eyes, and should be stored and disposed of properly to minimize environmental impact.

InChI:InChI=1/C12H9ClOS/c13-10-6-8-12(9-7-10)15(14)11-4-2-1-3-5-11/h1-9H

Upstream product

• 3085-42-5 bis(4-chlorophenyl)sulfoxide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 13343-26-5 phenyl p-chlorophenyl sulfide 
• 106-54-7 p-Chlorothiophenol 
• 1679-18-1 4-Chlorophenylboronic acid 
• 98-80-6 phenylboronic acid 
• 56075-36-6 1-(4-chlorophenyl)-2-(methylsulfonyl)diazene 
• 108-98-5 thiophenol 
• 882-33-7 diphenyldisulfane 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 66003-76-7 Diphenyliodonium triflate 
• 637-87-6 1-Chloro-4-iodobenzene 
• 30384-54-4 sodium S-(4-chlorophenyl) thiosulfate 
• 108-86-1 bromobenzene 

Downstream Products

• 2051-62-9 4'-biphenyl chloride 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 3085-42-5 bis(4-chlorophenyl)sulfoxide 

Relevant articles and documents

Aqueous sodium hypochlorite mediated chemoselective oxidation of chalcogenides to monoxides and dioxides by microwave exposure

A solvent-free, rapid, and highly selective oxidation of sulfides, selenides, and tellurides (chalcogenides) to the corresponding monoxides (sulfoxides, selenoxides, and telluroxides) or the corresponding dioxides (sulfones, selenones, and tellurones) has been developed using aqueous sodium hypochlorite on solid supports by exposure to microwave. Chemoselectivity and quantitative yields have been attained in most cases.

Mechanism of (salen)manganese(III)-catalyzed oxidation of aryl phenyl sulfides with sodium hypochlorite

The oxidation of 4-substituted phenyl phenyl sulfides was carried out with several oxo(salen)manganese( V) complexes in MeCN/H2O9 : 1. The kinetic data show that the reaction is first-order each in the oxidant and sulfide. Electron-attracting s

One-pot synthesis of aryl sulfoxides and sulfonium salts from sulfinic acid as a novel sulfurizing agent

Sodium sulfinate reacts electrophilically with aromatics in trifluoromethanesulfonic acid to give the corresponding aryl sulfoxides and sulfonium salts.

A selective and convenient oxidation of sulfides to sulfoxides with trichloroisocyanuric acid

Sulfides are readily oxidized to sulfoxides by a solution of pyridine, water, and trichloroisocyanuric acid in acetonitrile and methylene chloride.

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.

Selective oxidation of (hetero)sulfides with molecular oxygen under clean conditions

The development of eco-friendly and switchable catalytic systems for the conversion of a sole raw-material into distinct high-value products is a particularly attractive concept and a daunting synthetic challenge. In the present work, the first example of efficient and selective oxidation of sulfides to sulfones and sulfoxides using molecular oxygen under clean conditions was established.