1016232-57-7

Basic information

• Product Name: (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-hydroxy-pent-(1'E)-en-yl]-pregnane
• Synonyms: (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-hydroxy-pent-(1'E)-en-yl]-pregnane
• CAS NO: 1016232-57-7
• Molecular Weight: 370.532
• Mol File: 1016232-57-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-hydroxy-pent-(1'E)-en-yl]-pregnane(CAS DataBase Reference)
• NIST Chemistry Reference: (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-hydroxy-pent-(1'E)-en-yl]-pregnane(1016232-57-7)
• EPA Substance Registry System: (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-hydroxy-pent-(1'E)-en-yl]-pregnane(1016232-57-7)

Safety Data

• Hazardous Substances Data: 1016232-57-7(Hazardous Substances Data)

Upstream product

• 50-14-6 Calciferol 
• 115527-12-3 (20R)-des-A,B-8β-(benzoyloxy)-23,24-dinorcholan-22-al 
• 85769-75-1 (S)-3-hydroxybutyltriphenylphosphonium bromide 
• 66774-71-8 Benzoic acid (1R,3aR,4S,7aR)-7a-methyl-1-((S)-1-methyl-2-oxo-ethyl)-octahydro-inden-4-yl ester 
• 66774-70-7 (8S,20S)-des-A,B-8-benzoyloxy-20-(hydroxymethyl)-pregnane 
• 64190-52-9 (8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol 
• 98-88-4 benzoyl chloride 
• 145354-28-5 (20R)-des-A,B-8β-(benzoyloxy)-23,24-dinorcholane-22-ol 
• 59780-25-5 (S)-3-hydroxybutyl-triphenylphosphonium iodide 

Downstream Products

• 1016232-58-8 (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-(tertbutyldimethylsilyl)oxy-pent-(1'E)-en-yl]-pregnane 
• 1166870-22-9 (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-hydroxy-pentyl]-pregnane 
• 1166870-27-4 2-Methylene-(20S,25S)-19,26-dinor-1alpha,25-dihydroxyvitamin D₃ 
• 1166870-26-3 (20S,25S)-1α-[(tert-butyldimethylsilyl)oxy]-2-methylene-25-[(tert-butyldimethylsilyl)oxy]-19,26-dinorvitamin D3 tert-butyldimethylsilyl ether 
• 1166870-23-0 (8S,20S)-des-A,B-8-benzoyloxy-20-[(4'S)-(tert-butyldimethylsilyl)oxy-pentyl]-pregnane 

Relevant articles and documents

26-Desmethyl-2-methylene-22-ene-19-nor-1α,25-dihydroxyvitamin D 3 compounds selectively active on intestine

Six new analogs of 2-methylene-19-nor-1α,25-dihydroxyvitamin D 3, 6-7 and 8a,b-9a,b, have been synthesized. All compounds are characterized by a trans double bond located in the side chain between C-22 and C-23. While compounds 6 and 7 possess

Removal of the 26-methyl group from 19-nor-1α,25-dihydroxyvitamin D3 markedly reduces in vivo calcemic activity without altering in vitro VDR binding, HL-60 cell differentiation, and transcription

Twelve new analogues of 19-nor-1α,25-dihydroxyvitamin D3 (5-16) were prepared by convergent syntheses, employing the Wittig Horner reaction. The necessary Grundmann type ketones (45-48), possessing fixed configurations of the hydroxyl group at

2-Methylene-(20S,25S)-19,27-Dinor-(22E)-Vitamin D Analogs

This invention discloses 2-methylene-(20S,25S)-19,27-dinor-(22E)-vitamin D analogs, and specifically 2-methylene-(20S,25S)-19,27-dinor-(22E)-1α,25-dihydroxyvitamin D3, and pharmaceutical uses therefor. This compound exhibits pronounced activity