101870-46-6

Basic information

• Product Name: 3-(acetylamino)-4-chlorobenzoic acid
• Synonyms: 3-(acetylamino)-4-chlorobenzoic acid
• CAS NO: 101870-46-6
• Molecular Weight: 213.62
• Mol File: 101870-46-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(acetylamino)-4-chlorobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(acetylamino)-4-chlorobenzoic acid(101870-46-6)
• EPA Substance Registry System: 3-(acetylamino)-4-chlorobenzoic acid(101870-46-6)

Safety Data

• Hazardous Substances Data: 101870-46-6(Hazardous Substances Data)

Upstream product

• 96-99-1 4-chloro-3-nitrobenzoate 
• 533-17-5 N-(2-chlorophenyl)acetamide 
• 2840-28-0 3-amino-4-chloro-benzoic acid 
• 108-24-7 acetic anhydride 
• 99184-16-4 acetic acid-(2-chloro-5-chloroacetyl-anilide) 
• 56961-87-6 N-(2-chloro-3-methylphenyl)acetamide 

Downstream Products

• 1277132-62-3 C₁₅H₁₅ClN₂O₅ 
• 1277132-55-4 ethyl 3-acetamido-4-chloro-2-nitrobenzoate 
• 1277127-97-5 2-[4-chloro-3-(methylamino)-2-nitrobenzoyl]-5-methylcyclohexane-1,3-dione 
• 2840-28-0 3-amino-4-chloro-benzoic acid 
• 1277132-60-1 4-chloro-3-(methylamino)-2-nitrobenzoic acid 
• 1277132-57-6 ethyl 4-chloro-3-(methylamino)-2-nitrobenzoate 
• 1277132-56-5 ethyl 3-amino-4-chloro-2-nitrobenzoate 
• 284665-86-7 ethyl 3-acetamido-4-chlorobenzoate 

Relevant articles and documents

Investigations of Steric and Electronic Factors Influencing the Cyclopalladation of meta-Toluidine Analogues

The cyclopalladation of two different types of aniline derivatives is described: the acetylated anilines N-(3-methylphenyl)acetamide (2a), 3-(acetylamino)-4-chlorobenzoic acid (2c), and N-(2-chlorophenyl)acetamide (2d) are cyclometalated easily with palladium(II) acetate and trifluoroacetic acid to yield the corresponding complexes 4a, 4c, and 4d, respectively, whereas the acetylated meta-toluidine N-(2-chloro-5-methylphenyl)acetamide (2b) cannot be metalated at the only accessible site between the acetylamino and the methyl group.This aromatic C-H bond can be activated, however, with the second type of meta-toluidine derivatives: the 2-chloro-5,N-dimethyl-N-nitrosoaniline (3b) readily undergoes cyclopalladation to yield the corresponding Pd(II) complex di-μ-trifluoroacetato-bisdipalladium(II) (5b) containing a five-membered palladacylce with coordination of Pd(II) at the nitroso N-atom, which is established by 15N-NMR spectroscopy.