101906-25-6Relevant articles and documents
Total synthesis of (-)-xyloketal D and its enantiomer - Confirmation of absolute stereochemistry
Pettigrew, Jeremy D.,Freeman, Rebecca P.,Wilson, Peter D.
, p. 1640 - 1648 (2004)
The total synthesis of (-)-xyloketal D and its enantiomer have been achieved by the reaction of an orthoquinone methide with (4R)- and (4S)-4,5-dihydro-2,4-dimethylfuran via a diastereoselective inverse electron demand Diels-Alder reaction. This total syn
Synthesis of the C21-C28 segment of pectenotoxin-4
Kolakowski, Robert V.,Williams, Lawrence J.
, p. 4761 - 4764 (2008/02/07)
The synthesis of the C21-C28 segment of pectenotoxin-4 as the C21 Weinreb amide is described. Feasibility studies for the union of a related Weinreb amide and a functionalized alkyne are also reported.
The 3,4-Dihydro-2H-pyran Approach to (+)-Milbemycin β3. Part 2. An Improved Synthesis of (2R,4S,6S,8R,9S)-2--8,9-dimethyl-4-(dimethyl-t-butylsilyloxy)-1,7-dioxaspiroundecane
Kocienski, Philip J.,Street, Stephen D. A.,Yeates, Clive,Campbell, Simon F.
, p. 2189 - 2194 (2007/10/02)
A more efficient synthesis of the title compound (2), previously used in a total synthesis of (+)-milbemycin β3 (1), is described.The key step in the sequence involves a nucleophilic cleavage of the oxirane (4) by the organocuprate derived from