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(1R,2R)-2-isothiocyanato-N,N-diMethyl-CyclohexanaMin is a chemical compound belonging to the isothiocyanates family, characterized by the N=C=S functional group. It features a cyclohexylamine backbone with two methyl groups and an isothiocyanate functional group attached to the nitrogen atom. (1R,2R)-2-isothiocyanato-N,N-diMethyl-
CyclohexanaMin is widely used in organic synthesis and chemical reactions as a reagent or intermediate for creating various other compounds. Its properties and potential uses are determined by its structure and functional groups, making it a versatile and important compound in the field of organic chemistry.

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  • 1020665-66-0 Structure
  • Basic information

    1. Product Name: (1R,2R)-2-isothiocyanato-N,N-diMethyl- CyclohexanaMin
    2. Synonyms: (1R,2R)-2-isothiocyanato-N,N-diMethyl- CyclohexanaMin;(1R,2R)-2-Isothiocyanato-N,N-dimethylcyclohexanamine
    3. CAS NO:1020665-66-0
    4. Molecular Formula:
    5. Molecular Weight: 184.305
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1020665-66-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (1R,2R)-2-isothiocyanato-N,N-diMethyl- CyclohexanaMin(CAS DataBase Reference)
    10. NIST Chemistry Reference: (1R,2R)-2-isothiocyanato-N,N-diMethyl- CyclohexanaMin(1020665-66-0)
    11. EPA Substance Registry System: (1R,2R)-2-isothiocyanato-N,N-diMethyl- CyclohexanaMin(1020665-66-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1020665-66-0(Hazardous Substances Data)

1020665-66-0 Usage

Uses

Used in Organic Synthesis:
(1R,2R)-2-isothiocyanato-N,N-diMethyl-CyclohexanaMin is used as a reagent in organic synthesis for the creation of various other compounds. Its unique structure and functional groups make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Reactions:
In the chemical industry, (1R,2R)-2-isothiocyanato-N,N-diMethyl-CyclohexanaMin is used as an intermediate in various chemical reactions. Its isothiocyanate functional group allows it to participate in a range of reactions, such as nucleophilic addition, cycloaddition, and rearrangement reactions, contributing to the formation of diverse chemical products.
Used in Pharmaceutical Industry:
(1R,2R)-2-isothiocyanato-N,N-diMethyl-CyclohexanaMin is used as a building block in the development of pharmaceutical compounds. Its unique structure and reactivity make it suitable for the synthesis of drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, (1R,2R)-2-isothiocyanato-N,N-diMethyl-CyclohexanaMin is utilized as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its versatility in chemical reactions enables the development of effective and targeted agrochemical products.
Used in Specialty Chemicals:
(1R,2R)-2-isothiocyanato-N,N-diMethyl-CyclohexanaMin is also employed in the production of specialty chemicals, which are tailored for specific applications in various industries, such as coatings, adhesives, and polymers. Its unique properties and reactivity contribute to the development of innovative and high-performance specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 1020665-66-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,6,6 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1020665-66:
(9*1)+(8*0)+(7*2)+(6*0)+(5*6)+(4*6)+(3*5)+(2*6)+(1*6)=110
110 % 10 = 0
So 1020665-66-0 is a valid CAS Registry Number.

1020665-66-0Relevant articles and documents

Chiral amine-thioureas bearing multiple hydrogen bonding donors: Highly efficient organocatalysts for asymmetric Michael addition of acetylacetone to nitroolefins

Wang, Chun-Jiang,Zhang, Zhi-Hai,Dong, Xiu-Qin,Wu, Xiao-Jun

, p. 1431 - 1433 (2008/12/21)

New bifunctional organocatalysts amine-thioureas bearing multiple hydrogen bonding donors were synthesized and applied in catalytic asymmetric Michael addition of acetylacetone to aryl and alkyl nitroolefins. Multiple hydrogen bonding donors play a signif

Structural optimization of thiourea-based bifunctional organocatalysts for the highly enantioselective dynamic kinetic resolution of azlactones

Berkessel, Albrecht,Mukherjee, Santanu,Mueller, Thomas N.,Cleemann, Felix,Roland, Katrin,Brandenburg, Marc,Neudoerfl, Joerg-M.,Lex, Johann

, p. 4319 - 4330 (2008/09/18)

This article describes the synthesis of a library of structurally diverse bifunctional organocatalysts bearing both a quasi-Lewis acidic (thio)urea moiety and a Bronsted basic tertiary amine group. Sequential modification of the modular catalyst structure and subsequent screening of the compounds in the alcoholytic dynamic kinetic resolution (DKR) of azlactones revealed valuable structure-activity relationships. In particular, a "hit-structure" was identified which provides e.g. N-benzoyl-tert-leucine allyl ester in an excellent enantiomeric excess of 95%. The Royal Society of Chemistry 2006.

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