102129-05-5

Basic information

• Product Name: N-(1,1-dimethyl-2-piperidin-1-ylethyl)-N-pyridin-2-ylpropanamide
• CAS NO: 102129-05-5
• Molecular Formula: C₁₇H₂₇N₃O
• Molecular Weight: 289.4158
• Mol File: 102129-05-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 418.1°C at 760 mmHg
• Flash Point: 206.6°C
• Density: 1.056g/cm³
• Vapor Pressure: 3.37E-07mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: N-(1,1-dimethyl-2-piperidin-1-ylethyl)-N-pyridin-2-ylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,1-dimethyl-2-piperidin-1-ylethyl)-N-pyridin-2-ylpropanamide(102129-05-5)
• EPA Substance Registry System: N-(1,1-dimethyl-2-piperidin-1-ylethyl)-N-pyridin-2-ylpropanamide(102129-05-5)

Safety Data

• Hazardous Substances Data: 102129-05-5(Hazardous Substances Data)

Upstream product

• 17697-46-0 1,1-Dimethyl-1-nitro-2-piperidinoethan 
• 6105-74-4 2-methyl-1-(piperidin-1-yl)propan-2-amine 
• 109-04-6 2-bromo-pyridine 
• 79-03-8 propionyl chloride 
• 54151-65-4 2--pyridin 

Relevant articles and documents

Stereochemical researches about drugs. Part 11. Conformation of aminoalkyl acylamino-pyridines and their relation with morphine structure

The conformation of (R,S)-propiram and 8 analogues are investigated spectroscopically. Active analgesics are only found among the E-forms of the amides, in which the CH2 group of the propionyl substituent hangs over the pyridine ring - which itself stands vertical with respect to the planar amide group. The R-enantiomer of propiram is morphine-agonistic and corresponds to N-methylmorphinan in its spatial arrangement.