102261-80-3

Upstream product

• 6121-42-2 1-Phenyl-cyclopropanecarboxylic acid methyl ester 
• 6120-95-2 1-phenyl-1-cyclopropane carboxylic acid 
• 935-44-4 1-cyano-1-phenylcyclopropane 
• 140-29-4 phenylacetonitrile 
• 31729-66-5 1-phenyl-1-cyclopropanemethanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 850406-58-5 C₁₇H₁₇N₃O 
• 50462-74-3 Diethyl-(1-phenylcyclopropyl)methylmalonat 
• 850406-15-4 3-bromo-2-methyl-7-(1-phenyl-cyclopropylmethyl)-7H-imidazo[1,2-a]pyrazin-8-one 
• 102261-65-4 PtCl₂(C₅H₅N)2(CH₂C(C₆H₅)(CH₂OSO₂CH₃)CH₂) 

Relevant academic research and scientific papers

Electrophilic Bromolactonization of Cyclopropyl Diesters Using Lewis Basic Chalcogenide Catalysts

An efficient and regioselective electrophilic bromolactonization of cyclopropylmethyl diesters using triphenylphosphine sulfide (Ph3PS) or diphenyl selenide (Ph2Se) as the Lewis basic chalcogenide catalyst has been developed. It was observed that Ph3PS favored the formation of anti-diastereomer and yielded the multi-functional γ-lactones. Interestingly, the diastereoselectivity was reversed when using Ph2Se as a catalyst where the syn-product instead of the anti-product was favored. (Figure presented.).

IMIDAZO COMPOUNDS AND USES THEREOF

N-substituted imidazopyrazinone compounds such as N-alkylated/aralkylated 7H-imidazo[1,2-a]pyrazin-8-one compounds and related analogs are disclosed. Pharmaceutical compositions and kits containing the N-substituted imidazopyrazinone compounds, as well as therapeutic uses thereof, including treatment of arrhythmia, are also disclosed.