1026-21-7 Usage
General Description
1H-Indol-2-yl(p-tolyl) ketone is a chemical compound that belongs to the group of indoles, which are heterocyclic compounds containing a six-membered ring structure with a nitrogen atom. This specific compound has a ketone group attached to the indole ring, with a p-tolyl substituent at the 2-position of the indole. It is commonly used in organic synthesis and medicinal chemistry as a building block for various pharmaceuticals and biologically active molecules. The presence of the indole ring in this compound makes it suitable for the development of potential drug candidates targeting a wide range of biological activities, including anti-cancer, anti-inflammatory, and anti-microbial properties. Its versatile chemical structure makes it a valuable intermediate for the synthesis of diverse chemical compounds with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1026-21-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,2 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1026-21:
(6*1)+(5*0)+(4*2)+(3*6)+(2*2)+(1*1)=37
37 % 10 = 7
So 1026-21-7 is a valid CAS Registry Number.
1026-21-7Relevant articles and documents
Dual visible-light photoredox and palladium(II) catalysis for dehydrogenative C2-acylation of indoles at room temperature
Manna, Manash Kumar,Bairy, Gurupada,Jana, Ranjan
, p. 5899 - 5903 (2017)
A highly regioselective direct C2-acylation of N-pyrimidine protected indoles with aldehydes is reported at room temperature through the merger of visible light photoredox and palladium(ii) catalysis. Late-stage acylation of tryptophan, selective mono-acylation of carbazole and the syntheses of tubulin inhibitors D-64131 and D-68144 are also demonstrated.
Reaction of 3-(2-nitrophenyl)-1-arylprop-2-en-1-ones with triethylphosphite in microwave revisited: One-pot synthesis of 2-aroylindoles and 2-arylquinolines
Gupta, Annah,Khajuria, Rajni,Kapoor, Kamal K.
supporting information, p. 31 - 38 (2016/01/09)
One-pot synthesis of 2-aroylindoles and 2-arylquinolines has been achieved by the reductive cyclization of 3-(2-nitrophenyl)-1-arylprop-2-en-1-ones with triethylphosphite [P(OEt)3] under microwave irradiation. The formation of 2-arylquinolines by this method is unprecedented.
