1026085-87-9

Upstream product

• 622-59-3 1-isothiocyanato-4-methylbenzene 
• 179039-70-4 ethyl 2-(triphenylphosphoranylidene-amino)benzoate 
• 31162-13-7 2-azidobenzoic acid 
• 118-92-3 anthranilic acid 
• 622-58-2 p-Tolylisocyanate 

Downstream Products

• 22316-59-2 2-methyl-3-p-tolyl-4(3H)-quinazolinone 
• 37856-14-7 2-phenyl-3-(4-tolyl)quinazolin-4(3H)-one 
• 1414871-29-6 2-cyclohexyl-3-(4-tolyl)quinazolin-4(3H)-one 
• 1189260-75-0 2-ethenyl-3-(4-tolyl)quinazolin-4(3H)-one 
• 330829-50-0 2-butyl-3-(4-tolyl)quinazolin-4(3H)-one 
• 1597437-77-8 (E)-3-(2-((2-fluorobenzylidene)amino)ethyl)-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-78-9 (E)-3-[2-((3-hydroxy-4-methoxybenzylidene)amino)ethyl]-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-79-0 (E)-3-(2-((naphthalen-1-ylmethylene)amino)ethyl)-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-80-3 (E)-3-(2-((4-bromobenzylidene)amino)ethyl)-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-81-4 (E)-3-[2-((2-nitrobenzylidene)amino)ethyl]-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-82-5 (E)-3-[2-((3-nitrobenzylidene)amino)ethyl]-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-83-6 (E)-3-[2-((4-chlorobenzylidene)amino)ethyl]-2-(4-methylanilino)quinazolin-4(3H)-one 
• 1597437-67-6 3-(2-aminoethyl)-2-[4-methylanilino]quinazolin-4(3H)-one 
• 81905-02-4 2-(p-tolylamino)-4H-benzo[d][1,3]oxazin-4-one 

Relevant academic research and scientific papers

Novel 4(3H)-Quinazolinone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Bioactivity Evaluation

The aim of the present study is to design and synthesize a series of novel 4(3H)-quinazolinone derivatives containing an isoxazole moiety and evaluate their antifungal activity against Gibberella zeae (G. zeae), Fusarium oxysporum (F. oxysporum), Cytospor

Design, synthesis, and evaluation of new 4(3H)-quinazolinone derivatives containing a pyrazole carboxamide moiety

A total of 15 new 4(3H)-quinazolinone derivatives containing a pyrazole carboxamide moiety were designed and synthesized in this study. The structures of the target compounds were elucidated using 1H NMR, 13C NMR, MS, and elemental a

Design, synthesis, and antibacterial activity of novel Schiff base derivatives of quinazolin-4(3H)-one

Novel imine derivatives of quinazolin-4(3H)-one were designed and synthesized by using aminoethyl moieties to increase the amine bridge of quinazolin-4(3H)-one amine and then introducing various aromatic aldehydes. The target compounds were characterized

Functionalized carbodiimide mediated synthesis of 2,3-disubstituted quinazolin-4(3 H)-ones via the tandem strategy of C-nucleophilic addition and intramolecular NH-substitution cyclization

A facile synthesis of quinazolin-4(3H)-ones possessing carbon substituents at positions 2 and 3 has been developed. Key to the synthesis is a tandem strategy involving introduction of a 2-substituent and construction of the quinazolinone framework via C-nucleophilic addition to the carbodiimide cumulenic carbon followed by intramolecular nucleophilic substitution by the newly formed NH moiety at the proximal ester group.

Synthesis and fungicidal activities of 2-benzothiazolylthio-substituted 4H-imidazol-4-ones and 4(3H)-quinazolinones

4H-Imidazol-4-ones 4 or 4(3H)-quinazolinones 8 were synthesized by base catalytic reactions of 2-mercaptobenzothiazole with carbodiimides 2 or 6, respectively, which were obtained via aza-Wittig reaction of iminophosphorane 1 or 5 with aromatic isocyanates. 4 and 8 exhibited fungicidal activity.

Tetrabutylammonium fluoride promoted intramolecular nucleophilic attack of an ester group on a carbodiimide: Preparation of 1,3-oxazolin-5-ones and 3,1-benzoxazin-4-ones

Functionalized carbodiimides bearing an ester group either at the α or β position undergo cyclization in the presence of tetrabutylammonium fluoride (TBAF) under mild conditions to give 1,3-oxazolin-5-ones or 3,1-benzoxazin-4-ones in synthetically useful yields.