10294-29-8Relevant academic research and scientific papers
Vaporization and vapor complexation in the gold(III) chloride-aluminum(III) chloride system
Nalbandian,Boghosian,Papatheodorou
, p. 1769 - 1773 (1992)
The vapors over solid gold(III) chloride and the vapor-phase equilibria of the gold(III) chloride-alummum(III) chloride binary system have been investigated spectrophotometrically. The thermodynamic functions of the sublimation 2AuCl3(s) = Au2Cl6(g) were determined: ΔHS° = 114.2 ± 1.8 kJ mol-1 and ΔSS° = 160.5 ± 3.3 J mol-1 K-1 (480 3(s) + 1/2Al2Cl6(g) = AuAlCl6(g) with ΔHR° = 59.9 ± 0.8 kJ mol-1 and ΔSR° = 91.5 ± 1.6 J mol-1 K-1 (470 2Cl6(g) pressure the volatility enhancement of AuCl3 is ～300. The electronic absorption spectra of the Au2Cl6(g) and AuAlCl6(g) molecules were interpreted in terms of a distorted square planar geometry of Au(III). Bridged and terminal ligand-to-metal charge-transfer bands were indentified in the spectra.
Coordination of pyridinethiols in gold(I) complexes
Raeisaenen, Minna T.,Runeberg, Nino,Klinga, Martti,Nieger, Martin,Bolte, Michael,Pyykkoe, Pekka,Leskelae, Markku,Repo, Timo
, p. 9954 - 9960 (2007)
High-yield synthesis of gold(I) thionato complexes, bis(pyridine-2- thionato)gold(I) chloride (1) and bis(pyridine-4-thionato)gold(I) chloride (2), are described. According to their solid-state structures, a linear coordination of Au(I), equiplanar coordination of the ligands and two weak γ-agostic interactions are found in both of these complexes despite of different relative positions of N and S atoms in the pyridinethionato ligands. Density functional theory calculations on 1 and 2 reproduce the observed X-ray structures. Even though the C-H...Au interactions of Au(I) and two pyridine moieties (2.83 and 2.88 A in 1 and 2.86 A in 2) are relatively weak, according to calculations they seem to provide further stabilization for the coordination and orientation of the ligands. In 1 the shortest Au...Au distances of 3.50 A indicate that aurophilic interactions, even though weak, are present in the solid state, whereas in 2 these interactions are absent.
Synthesis and Structure-Activity Relationship Study of Antimicrobial Auranofin against ESKAPE Pathogens
Wu, Bin,Yang, Xiaojian,Yan, Mingdi
, p. 7751 - 7768 (2019/09/10)
Auranofin, an FDA-approved arthritis drug, has recently been repurposed as a potential antimicrobial agent; it performed well against many Gram-positive bacteria, including multidrug resistant strains. It is, however, inactive toward Gram-negative bacteria, for which we are in dire need of new therapies. In this work, 40 auranofin analogues were synthesized by varying the structures of the thiol and phosphine ligands, and their activities were tested against ESKAPE pathogens. The study identified compounds that exhibited bacterial inhibition (MIC) and killing (MBC) activities up to 65 folds higher than that of auranofin, making them effective against Gram-negative pathogens. Both thiol and the phosphine structures influence the activities of the analogues. The trimethylphosphine and triethylphosphine ligands gave the highest activities against Gram-negative and Gram-positive bacteria, respectively. Our SAR study revealed that the thiol ligand is also very important, the structure of which can modulate the activities of the AuI complexes for both Gram-negative and Gram-positive bacteria. Moreover, these analogues had mammalian cell toxicities either similar to or lower than that of auranofin.
NOVEL METHOD FOR PRODUCING NON-CYANOGEN GOLD COMPOUND
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Paragraph 0019, (2018/09/12)
PROBLEM TO BE SOLVED: To provide a novel method for producing a useful non-cyanogen gold compound that is available as a gold supply source for electroless and electrolytic plating liquids and contains no cyanogen. SOLUTION: The non-cyanogen gold compound represented by formula (2) can be produced in a good yield by adjusting an aqueous solution of a gold compound represented by formula (1) to a pH of 7.0 to 14.0 and keeping the temperature at 0 to 100°C; adding to the solution a solution dissolving 2-mercaptobenzothiazoles in an aqueous solution of one kind or two or more kinds selected from sodium hydroxide, potassium hydroxide and calcium hydroxide; and reacting them for 1 to 15 minutes. (1) (M is NH4, Na or K; x>0, y>0, a>0, b>0, x+y+a+b-1>1.) (2) (R1 to R4 are H, a halogen atom, -(CH2)nCH3/(n=0 to 6), -O-(CH2)nCH3/(n=0 to 6) or -NO2). SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
New production of gold resinate
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Paragraph 0017, (2017/03/23)
PROBLEM TO BE SOLVED: conventional gold resinate paste by improving the difficulty in firing temperature of 450 °C fired during low temperature of the mold has a sheet resistance which is suitable for forming a film of gold resinate paste to provide a novel method for manufacturing the metal resinate. SOLUTION: a metallic compound represented by general eq. (1) pH7.0-14.0 aq. 0 °C -100 ° C is adjusted to keep the temperature, this soln. mercaptocarboxylic acetic acid, 3-mercapto propionate, mercaptocarboxylic hydroxybutanoate 4-, 5-and 6-mercaptocarboxylic hydroxyhexanamide mercaptocarboxylic Pentaenoic acid selected from 1-15 min. mercaptocarboxylic acid is added to the reaction expressed by the general eq. (2) can be obtained in high yield of gold resinate Selected drawing: no
NON-CYANIDE GOLD COMPOUND
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Paragraph 0017, (2017/02/28)
PROBLEM TO BE SOLVED: To provide a non-cyanide gold compound having no cyan useful as a gold source for non-electrolytic and electrolytic plating liquid. SOLUTION: There is provided a white powdery crystal of a non-cyanide gold compound by suspending alkali metal salts such as first gold chloride, sodium chloride and potassium chloride and 2-mercaptobenzothiazoles in an aqueous solution, then reacting them under a condition of pH of 7.0 to 13.5 and temperature of 10 to 90°C in a presence of inert gas, column purifying deposited crystal by benzene after a reaction end to coordinate 2-mercaptobenzothiazoles to a gold ion represented by the general formula (1). (1), where R1 to R4 are H, a halogen atom, -CH3, -OCH3 or -NO2. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
MANUFACTURING METHOD OF GOLD COMPOUND
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Paragraph 0019, (2017/02/28)
PROBLEM TO BE SOLVED: To provide a gold compound having no cyan useful as a gold source for non-electrolytic and electrolytic plating liquid. SOLUTION: There is provided a gold compound represented by the general formula (1), which is a crystal obtained by suspending alkali metal salts such as sodium first gold compound chloride synthesized form chloroauric acid, alkali metal salt and an organic compound having a thiol group in an aqueous solution, then reacting them under a condition of pH of 7.0 to 13.5 and temperature of 10 to 90°C in a presence of inert gas such as argon gas or nitrogen gas, column purifying deposited crystal by alcohol after a reaction end. The gold compound is available as a gold source for non-electrolytic and electrolytic plating liquid having no cyan in a plating bath. (1), where R represents a monovalent alkyl group, an aryl group, an alkenyl group, a silyl group, an alkynyl group and a monovalent hydrocarbon cyclic or heterocyclic aromatic organic group and a part of hydrogen atoms on a ring may be substituted by a group which has no participation in a reaction. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
MANUFACTURING METHOD OF NON-CYANIDE GOLD COMPOUND FOR GOLD PLATING
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Paragraph 0017, (2017/03/08)
PROBLEM TO BE SOLVED: To provide a manufacturing method of a gold compound having no cyan available as a gold source for non-electrolytic and electrolytic plating liquid. SOLUTION: There is provided a non-cyanide gold compound represented by the general formula (1), which is a white powdery crystal obtained by suspending alkali metal salts such as sodium first gold compound chloride synthesized form chloroauric acid, potassium chloride and 2-mercaptobenzothiazoles in an aqueous solution, then reacting them under a condition of pH of 7.0 to 13.5 and temperature of 10 to 90°C in a presence of inert gas such as argon gas or nitrogen gas, column purifying deposited crystal by benzene after a reaction end. The non-cyanide gold compound is available as a gold source for non-electrolytic and electrolytic plating liquid having no cyan in a plating bath. General formula (1), where R1 to R4 are H, a halogen atom, -CH3, -OCH3, -NO2. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPO&INPIT
METHOD FOR PRODUCING GOLD RESINATE
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Paragraph 0013; 0015, (2017/03/17)
PROBLEM TO BE SOLVED: To provide a method for producing a gold resinate suitable for gold resinate paste capable of forming a gold film having resistance even by low temperature firing at 250°C or lower by improving the hard points upon high temperature firing of gold resinate paste. SOLUTION: A gold resinate is obtained by adding aurous chloride synthesized from chlorauric acid, alkali metal salt such as sodium chloride and potassium chloride and mercaptocarboxylic acid or the like into pure water so as to be a mixed liquid, regulating the mixed liquid at a pH of 7.0 to 13.5 while bubbling an inert gas such as an argon gas and a nitrogen gas and holding the reaction system at 10 to 90°C for several hours so as to obtain a gold resinate. According to this production method, the need of only the one where aurous chloride, alkali metal chloride and mercaptocarboxylic acid are beforehand made into a mixed solution, and the reaction is progressed, and fine regulation such as the addition velocity, reaction velocity and reaction temperature of starting raw material is made needless. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
ORGANOGOLD COMPLEX
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Paragraph 0017, (2017/01/02)
PROBLEM TO BE SOLVED: To provide an organogold complex free from cyanogen that is useful as a gold supply source for electroless and electrolytic plating liquid. SOLUTION: An organogold complex is obtained by coordinating a 2-benzimidazole thiol to a gold ion represented by the following general formula (1) (where R1-R4 are a hydrogen atom, a halogen atom, -CH3, -OCH3, or -NO2). COPYRIGHT: (C)2016,JPOandINPIT
