105151-39-1

Basic information

• Product Name: 5-Ethylpyridine-2,3-dicarboxylic acid diethyl ester
• Synonyms: 5-ETHYLPYRIDINE-2,3-DICARBOXYLIC ACID DIETHYL ESTER;Diethyl 5-ethylpyridine-2,3-dicarboxylate;5-ETHYL-2,3-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER;5-Ethyl-Pyridine-2,3-Dicarboxy;5-ETHYL -PAYIDINE-2,3-DICARBOXYLIC ACID DIETHYL ESTER 98+%;2,3-Pyridinedicarboxylicacid, 5-ethyl-, 2,3-diethyl ester;Imazethapyr Impurity (Diethyl 5-ethylpyridine-2,3-dicarboxylate);dimethyl 5-ethylpyridine-2,3-dicarboxylate
• CAS NO: 105151-39-1
• Molecular Formula: C₁₃H₁₇NO₄
• Molecular Weight: 251.28
• Product Categories: Esters;Pyridines;Pyridine;Organic acids
• Mol File: 105151-39-1.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 351.596 °C at 760 mmHg
• Flash Point: 166.44 °C
• Appearance: white crystal
• Density: 1.12 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.507
• Storage Temp.: 2-8°C
• Solubility: DMSO, Methanol (Slightly)
• PKA: -0.20±0.10(Predicted)
• CAS DataBase Reference: 5-Ethylpyridine-2,3-dicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Ethylpyridine-2,3-dicarboxylic acid diethyl ester(105151-39-1)
• EPA Substance Registry System: 5-Ethylpyridine-2,3-dicarboxylic acid diethyl ester(105151-39-1)

Safety Data

• Hazard Codes: F
• Hazardous Substances Data: 105151-39-1(Hazardous Substances Data)

Usage

Uses

Diethyl 5-Ethylpyridine-2,3-dicarboxylate is used as a reagent for the preparation of midazolinylpyridinecarboxylic acid from pyridinedicarboxylate and aminobutyramide.

InChI:InChI=1/C13H17NO4/c1-4-9-7-10(12(15)17-5-2)11(14-8-9)13(16)18-6-3/h7-8H,4-6H2,1-3H3

Upstream product

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• 64-17-5 ethanol 
• 102268-15-5 5-ethyl-2,3-pyridinedicarboxylic acid 
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Downstream Products

• 81335-77-5 imazethapyr 

Relevant articles and documents

Synthesis of diethyl 5-Ethyl-2,3-Pyridinedicarboxylate

Diethyl 5-ethyl-2,3-pyridinedicarboxylate was synthesized using ammonium acetate as the nitrogen source. The optimum process conditions were obtained by exploring the reaction mechanism and researching the effects of reactant ratio, reaction temperature and solvent amount on the yield from all sides. Diethyl 5-ethyl-2,3-pyridinedicarboxylate yield was 98 % analysis by HPLC and the overall yield 96.8 % calculated by 2-chloro-3-oxo-succinic acid diethyl ester. The optimum process has the advantages of available initial material, simple waste-water treatment and environmental friendliness which are more applicable for industrial production.

Preparation method for imidazolinone compound

The invention provides a preparation method for an imidazolinone compound, belongs to the technical field of organic synthesis, and can solve the problems that a large amount of wastewater is producedand the content of impurities in the product is high in the existing process for preparing the imidazolinone compound. According to the preparation method for the imidazolinone compound provided by the invention, a solution of 5-alkyl pyridine-2,3-phthalate is synthesized from ammonium carbonate; the steps of adding water, extracting, refining and the like are avoided in post-treatment; the obtained solution of the 5-alkyl pyridine-2,3-phthalate is used for subsequent reaction; and the wastewater is not produced. Then, a catalyst is added in the process of preparing 5-alkyl pyridine-2,3-dimethylbenzene anhydride, and the pH is controlled in the subsequent reaction process, so that the production of the impurities can be avoided, and the product purity is improved. The imidazolinone compound prepared by the method provided by the invention can be used as a high-efficiency herbicide.

Process for preparing pyridinecarboxylic acid derivatives

The present invention pertains to a method of preparing substituted and unsubstituted N-hydroxy-2-aminobutane diacid derivatives. The invention also pertains to the use of N-hydroxy-2-aminoethane derivatives (including the N-hydroxy-2-aminobutane diacid derivatives) in the preparation of pyridine derivatives.