10333-68-3Relevant academic research and scientific papers
Copper(II)-mediated regioselective N-arylation of pyrroles, indoles, pyrazoles and carbazole via dehydrogenative coupling
Sadhu, Pradeep,Punniyamurthy, Tharmalingam
, p. 2803 - 2806 (2016)
A copper(ii)-mediated regioselective N-arylation of azoles has been developed using 8-aminoquinoline amide as a directing group. This reaction shows a broad substrate scope with different azoles such as pyrroles, indoles, pyrazoles and carbazole with good
Br?nsted Acid-Catalyzed Asymmetric Ring-Closing Alkylation of Inert N-substituted Pyrroles with α, β-Unsaturated Ketones
Wei, Zhao,Zhang, Jinlong,Yang, Huameng,Jiang, Gaoxi
supporting information, p. 3694 - 3697 (2019/07/12)
A Chiral Br?nsted acid catalyzed asymmetric intramolecular ring-closing alkylation of inert pyrroles with α, β-unsaturated ketones has been developed. This approach gave a wide range of 4-phenyl-4,5-dihydro-6H-benzo[f]pyrrolo[1,2-a]azepin-6-ones in high yields with good enantioselectivities under mild reaction conditions. (Figure presented.).
Active manganese dioxide promoted cyclization of ortho-(1H-pyrrol-1-yl)aryl and heteroaryl carboxylic acids to 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one derivatives
Grande, Fedora,Brizzi, Antonella,Garofalo, Antonio,Aiello, Francesca
, p. 9951 - 9956 (2013/11/06)
The hitherto unknown lactone 5H-pyrrolo[1,2-a][3,1]benzoxazin-5-one and six of its substituted derivatives have been prepared by active manganese dioxide promoted oxidative cyclization of the corresponding 2-(1H-pyrrol-1-yl)benzoic acids, under mild conditions, in moderate yields. The method was successfully extended to the cyclization of some ortho-(1H-pyrrol-1-yl)heteroaryl carboxylic acids and 2-(1H-indol-1-yl)benzoic acids.
Tricyclic oxime ethers
-
, (2008/06/13)
The present invention relates to compounds of formula (I): STR1 wherein A, x, y, R1, R2 and R3 are as defined in the description. The compounds are useful for treating diseases requiring a selective serotonin reuptake site
N-phenylpyrrole: A kinetic, though not thermodynamic preference for dilithiation
Faigl,Schlosser
, p. 10271 - 10278 (2007/10/02)
Under appropriate conditions the clean preparation of either the α-monolithiated or the o,α-dilithiated derivative of N-phenylpyrrole is possible. In the latter case, the first deprotonation occurs at the α-position. Dimetalation is kinetically but not thermodynamically favored.
The Preparation of 2,3-Dihydro-1H-pyrroloindole, 2,3-Dihydro-9-methyl-1H-pyrroloindole, 1,2,2a,3,4,5-hexahydropyrrolocarbazole, and 2,3,3a,4,5,6-hexahydro-1H-pyridocarbazole
Bailey, A. Sydney,Scott, Peter W.,Vandrevala, Marazban H.
, p. 97 - 101 (2007/10/02)
Several routes for the preparation of the four compounds listed in the title have been investigated to decide on methods suitable for obtaining the materials in quantity.
Oral hypoglycemic agents: 1(2 carboxyphenyl)pyrroles
Sugihara,Matsumoto,Hamuro,Kawamatsu
, p. 1560 - 1563 (2007/10/06)
A series of 1 (2 carboxyphenyl) pyrroles and their cyclized derivatives, pyrrolo [1,2 a]indoles, was synthesized and screened for hypoglycemic activity in rats. 1 (2 Carboxy 3 chlorophenyl) pyrrole was the most active, but had side effects.
