10354-29-7Relevant articles and documents
Hantzsch 1,4-dihydropyridine synthesis in aqueous ethanol by visible light
Ghosh, Somnath,Saikh, Forid,Das, Jhantu,Pramanik, Arun Kumar
, p. 58 - 62 (2013)
A highly efficient environment-friendly Hantzsch 1,4-dihydropyridine synthesis under visible light in aqueous ethanol has been achieved in excellent yield via a one-pot three component reaction of various types of aliphatic and aromatic aldehydes with ethyl acetoacetate and ammonium hydroxide solution.
2-Hydroxyethylammonium acetate: An efficient and reusable homogeneous catalyst for the synthesis of Hantzsch 1, 4-dihydropyridines
Kang, Li-Qin,Cao, Zhi-Jun,Lei, Ze-Jun
, p. 1125 - 1128 (2016)
2-Hydroxyethylammonium acetate ionic liquid was found to be an excellent catalyst for the one-pot synthesis of 1,4-dihydropyridine derivatives via Hantzsch reaction of ethyl acetoacetate or acetoacetanilide, ammonium acetate, and various aromatic aldehyde
Silica sulfuric acid: An efficient heterogeneous catalyst for the one-pot synthesis of 1,4-dihydropyridines under mild and solvent-free conditions
Datta, Bandita,Pasha, M. Afzal
, p. 1180 - 1184 (2011)
A series of 1,4-dihydropyridines have been prepared by a one-pot condensation of aldehydes, ethyl acetoacetate, and ammonium acetate in the presence of a heterogeneous catalyst silica sulfuric acid at room temperature under solvent-free condition. This new protocol has the advantage of short reaction time and excellent yields, and is an environmentally benign route to the synthesis of 1,4-dihydropyridines.