10371-49-0

Basic information

• Product Name: 1-phenyl-1-(phenylthio)-2-propenone
• Synonyms: 1-phenyl-1-(phenylthio)-2-propenone
• CAS NO: 10371-49-0
• Molecular Weight: 242.342
• Mol File: 10371-49-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-phenyl-1-(phenylthio)-2-propenone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-1-(phenylthio)-2-propenone(10371-49-0)
• EPA Substance Registry System: 1-phenyl-1-(phenylthio)-2-propenone(10371-49-0)

Safety Data

• Hazardous Substances Data: 10371-49-0(Hazardous Substances Data)

Upstream product

• 3893-35-4 1-diazo-1-phenyl-2-propanone 
• 108-98-5 thiophenol 
• 89036-90-8 2-Methoxy-1-phenyl-2-phenylsulfanyl-ethanol 
• 35874-96-5 Phenyl(phenylthio)acetaldehyd 
• 111198-03-9 1-((phenylthio)methyl)-1H-benzo[d][1,2,3]triazole 
• 98-86-2 acetophenone 
• 69753-43-1 1-chloro-1-phenylthio-2-propanone 
• 71-43-2 benzene 
• 882-33-7 diphenyldisulfane 
• 103-79-7 1-phenyl-acetone 
• 115205-58-8 1-Phenyl-1-phenylsulfanyl-propan-2-ol 
• 930-69-8 sodium thiophenolate 
• 22596-45-8 2-methyl-2-nitro-3-phenyloxirane 

Downstream Products

• 69798-74-9 1-chloro-1-phenyl-1-phenylthio-2-propanone 
• 115205-59-9 (E)-3-Methyl-4-phenyl-4-phenylsulfanyl-but-3-enoic acid ethyl ester 
• 103-79-7 1-phenyl-acetone 
• 40394-84-1 3-Methyl-4-oxo-4-phenyl-butansaeure-ethylester 
• 53258-89-2 1-acetoxy-1-phenyl-1-phenylthio-2-propanone 

Relevant articles and documents

Novel and efficient insertions of carbons carrying O-, S-, and N-Linked substituents: Synthesis of α-alkoxyalkyl, α-(Alkylthio)alkyl, and α-(Carbazol-9-yl)alkyl ketones

A wide variety of benzotriazolyl-stabilized anions 2, obtained by the lithiation of 1-(α-alkoxyalkyl)-, 1-[α-(alkylthio)alkyl]-, and 1-[α-(carbazol-9-yl)alkyl]benzotriazoles 1, on reaction with aliphatic and aromatic aldehydes and ketones, followed by rearrangement induced by heating in the presence of zinc bromide, furnish one-carbon-homologated α-alkoxyalkyl, α-(alkylthio)alkyl, and α-(carbazol-9-yl)alkyl ketones 4 in simple one-pot operations in good yields with excellent regioselectivity. In several alkoxymethylene insertions, intermediate 2-alkoxyoxiranes were separated in good yields, demonstrating the epoxide mechanism for the rearrangements and providing a facile approach to poly substituted 2-alkoxyoxiranes, another class of important compounds.

α-Thiocarbonyl synthesis via the FeII-catalyzed insertion reaction of α-diazocarbonyls into S-H bonds

Fe(OTf)2 was used to catalyze the insertion reaction of α-diazocarbonyls into S-H bonds at 40 °C. A wide range of α-thioesters were obtained in yields up to 96% within 24-48 h from their corresponding α-diazoesters. A variety of thiols were use

REGIOSPECIFIC SYNTHESIS OF α-(PHENYLTHIO)CYCLOALKENONES AND OF α-PHENYL-α-(PHENYLTHIO)KETONES VIA αα-ADDITION OF PHENYLSULPHENYL CHLORIDE TO α-DIAZOKETONES

Cyclic α-diazoketones react with phenylsulphenyl chloride at room temperature to furnish α-chloro-α-(phenylthio)cycloalkanones which undergo ready dehydrochlorination to α-(phenylthio)cycloalkenones when treated with triethylamine; acyclic, terminal α-diazoketones also furnish α-chloro-α-(phenylthio)adducts which are useful electrophiles in the synthesis of α-phenyl-α-(phenylthio)ketones.