103747-96-2Relevant academic research and scientific papers
New C2-symmetric six-membered carbene ligands incorporating two hydroxyl groups for palladium-catalyzed deprotonative-cross-coupling processes (DCCP) of sp3 C–H bonds in diarylmethanes
Zhou, Bi-Hui,Wu, Chen,Chen, Xing-Xiu,Huang, Hong-Xia,Li, Lin-Lin,Fan, Li-Mei,Li, Jie
, p. 4157 - 4161 (2017)
A series of novel 3,4,5,6-tetrahydropyrimidinium salts, the precursor of N-heterocyclic carbene, were synthesized in high yields using a two-step procedure starting from commercially available amino alcohols. In situ prepared corresponding carbenes were tested in palladium-catalyzed C(sp3)?H arylation of 4-benzylpyridine with aryl bromides, affording triarylmethane derivatives in high yields.
Screening of C2-symmetric chiral phosphinites as ligands for ruthenium(II)-catalyzed asymmetric transfer hydrogenation of prochiral aromatic ketones
Elma, Duygu,Durap, Feyyaz,Aydemir, Murat,Baysal, Akin,Meric, Nermin,Ak, Bünyamin,Turgut, Ylmaz,Gümgüm, Bahattin
, p. 46 - 52 (2013/08/25)
Metal-catalyzed transfer hydrogenation processes provide a widely-used alternative to direct hydrogenation processes of ketones. As part of an ongoing program, we report enantioselective C2-symmetric bis(phosphinite)- ruthenium(II) catalytic systems for the transfer hydrogenation of prochiral aromatic ketones. The new catalytic systems can readily be formed under in situ conditions from C2-symmetric chiral bis(phosphinite) ligands and [Ru(η6-p-cymene)(μ-Cl)Cl]2 in transfer hydrogenation reaction media. These chiral ruthenium catalytic systems serve as catalyst precursors for the asymmetric transfer hydrogenation of acetophenone derivatives in iso-PrOH and giving the corresponding optical active secondary alcohols up to 94% ee.
Asymmetric conjugate addition to cyclic enone catalyzed by Cu-NHC complexes with C2 symmetry
Shan, Fengjun,Jiang, Lan,Li, Zhengning,Zhao, Defeng
scheme or table, p. 973 - 977 (2012/01/05)
A series of chiral, C2 symmetric tridentate N-heterocyclic carbene precursors, containing two N-functionalized hydroxyl or alkoxyl groups, were synthesized. They were applied to catalyze the asymmetric conjugate addition of diethylzinc to cyclo
New enantiopure imidazolinium carbene ligands incorporating two hydroxy groups for Lewis acid-catalyzed diethyl zinc addition to aldehydes
Gilani, Mazhar,Wilhelm, Rene
experimental part, p. 2346 - 2352 (2009/04/11)
New enantiopure imidazolinium carbene ligands incorporating two hydroxy functions have been synthesized from commercially available chiral amino alcohols and diamines. These ligands in combination with different metallic salts have been investigated in th
Chiral (Macrocyclic) Sulfide- and Sulfide/Alkylamino-Containing Ligands for Nickel-Catalyzed Grignard Cross-Coupling Reactions
Vriesema, Bindert K.,Lemaire, Marc,Buter, Jan,Kellogg, Richard M.
, p. 5169 - 5177 (2007/10/02)
Some macrocycles that contain sulfide and/or amino linkages as coordination sites have been examined as ligands for the nickel-catalyzed cross-coupling of the Grignard reagent of 1-phenyl-1-chloroethane with vinyl vromide to provide (1-methyl-2-propenyl)b
MACROCYCLES WITH SULFIDE AND AMINE BINDING SITES AS CHIRAL LIGANDS FOR NICKEL CATALYZED CROSS COUPLING OF A GRIGNARD REAGENT WITH VINYL BROMIDE
Lemaire, Marc,Vrisema, Bindert K.,Kellogg, Richard M.
, p. 3499 - 3502 (2007/10/02)
Syntethic routes to macrocycles derived from (S)-phenyl alanine and (S)-cysteine have been developed.The catalyzed coupling of the Grignard reagent of 1-chloro-1-phenylethane and vinyl bromide in the presence of these ligands proceeds usually in good yields and in enantiomeric excesse (e.e.) of up to 46percent.
