1038915-92-2

Basic information

• Product Name: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate
• CAS NO: 1038915-92-2
• Molecular Weight: 420.511
• Mol File: 1038915-92-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate(1038915-92-2)
• EPA Substance Registry System: tert-butyl 3-(4-(7-carbamoyl-2H-indazol-2-yl)phenyl)piperidine-1-carboxylate(1038915-92-2)

Safety Data

• Hazardous Substances Data: 1038915-92-2(Hazardous Substances Data)

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 1056971-32-4 tert-butyl-3-phenylpiperidine-1-carboxylate 
• 132874-06-7 methyl 3-(bromomethyl)-2-nitrobenzoate 
• 875798-79-1 3-(4-aminophenyl)piperidine-1-carboxylic acid tert-butyl ester 
• 750585-94-5 2-bromo-3-formyl-benzoic acid methyl ester 
• 1038915-90-0 methyl 2-{4-[1-(tert-butoxycarbonyl)piperidin-3-yl]phenyl}-2H-indazole-7-carboxylate 
• 77287-34-4 formamide 
• 138229-59-1 3-formyl-2-nitrobenzoic acid methyl ester 
• 5471-82-9 methyl 3-methyl-2-nitrobenzoate 
• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 1038915-99-9 tert-butyl 3-[4-({[3-(methoxycarbonyl)-2-nitrophenyl]methylene}amino)phenyl]piperidine-1-carboxylate 

Downstream Products

• 1038915-56-8 racemic 3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidinium chloride 
• 1038915-60-4 (3S)-3-[4-{7-(aminocarbonyl)-2H-indazol-2-yl}phenyl]piperidine 
• 1038915-58-0 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide 

Relevant articles and documents

Indazole formamide compound as well as preparation method and application thereof

The invention belongs to the field of chemical medicines, and particularly relates to an indazole formamide compound as well as a preparation method and application thereof. The invention provides anindazole carboxamide compound or a pharmaceutically acce

Synthesis method for preparing PARP inhibitor Niraparib

The invention provides a novel synthesis method for preparing a PARP inhibitor Niraparib. The method comprises the steps that a starting material methyl anthranilate is subjected to diazo coupling, cyclization, amidation, BOC removal and chiral resolution, and then the Niraparib with the purity reaching 99.5% is obtained. The method is simple, convenient and easy to operate suitable for industrial production.

Niraparib synthesis method

The invention discloses a Niraparib synthesis method. The method comprises that through esterification, 3-methyl hydroformylation, 3-schiff base reaction, cyclization, amidation, BOC removal and chiral resolution, optically pure Niraparib with purity of 91% or more is prepared from 3-methyl-2-nitrobenzoic acid. The method has the advantages of simple process, high efficiency, easy operation and less equipment requirement, and is a method suitable for industrial production.