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103914-44-9

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103914-44-9 Usage

Chemical compound

6-FLUORO-2-PHENYL-4-QUINOLINOL

Classification

Quinolone class of antibiotics

Use

Treatment of various bacterial infections

Composition

Contains a fluorine atom, a phenyl group, and a quinolinol ring structure

Mechanism of action

Inhibits bacterial DNA synthesis by targeting essential enzymes

Spectrum of activity

Broad spectrum against both Gram-negative and Gram-positive bacteria

Caution

Should be used under the guidance of a healthcare professional to avoid resistance and side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 103914-44-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,9,1 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 103914-44:
(8*1)+(7*0)+(6*3)+(5*9)+(4*1)+(3*4)+(2*4)+(1*4)=99
99 % 10 = 9
So 103914-44-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H10FNO/c16-11-6-7-13-12(8-11)15(18)9-14(17-13)10-4-2-1-3-5-10/h1-9H,(H,17,18)

103914-44-9 Well-known Company Product Price

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  • Aldrich

  • (BBO000293)  6-Fluoro-4-hydroxy-2-phenylquinoline  AldrichCPR

  • 103914-44-9

  • BBO000293-1G

  • 2,255.76CNY

  • Detail

103914-44-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-fluoro-2-phenyl-1H-quinolin-4-one

1.2 Other means of identification

Product number -
Other names 6-Fluoro-2-phenyl-4-quinolinol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103914-44-9 SDS

103914-44-9Relevant articles and documents

Supported palladium-catalyzed carbonylative cyclization of 2-bromonitrobenzenes and alkynes to access quinolin-4(1H)-ones

Li, Chenyu,Li, Chuan-Ying,Lu, Wangyang,Wang, Jian-Shu,Wu, Xiao-Feng,Xu, Tiefeng,Ying, Jun

, p. 81 - 87 (2022/03/15)

A palladium supported on graphitic carbon nitride (Pd/g-C3N4) catalyzed carbonylative cyclization of 2-bromonitrobenzenes and alkynes has been developed for the expedite construction of quinolin-4(1H)-one scaffolds. By using a low loading heterogeneous palladium catalyst, Mo(CO)6 as both the CO surrogate and the reductant, and nitroarenes as the nitrogen source, the reaction proceeded well to give a variety of quinolin-4(1H)-ones in good to excellent yields.

Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: Identification as antimitotic agents interacting with tubulin

Kuo,Lee,Juang,Lin,Wu,Chang,Lednicer,Paull,Lin,Hamel,Lee

, p. 1146 - 1156 (2007/10/02)

A series of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds have been synthesized and evaluated as cytotoxic compounds and as antimitotic agents interacting with tubulin. The 2-phenyl-4-quinolones (22-30) with substituents

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