1039454-77-7

Basic information

• Product Name: N-(4-acetylbenzyl)benzamide
• Synonyms: N-(4-acetylbenzyl)benzamide
• CAS NO: 1039454-77-7
• Molecular Weight: 253.301
• Mol File: 1039454-77-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(4-acetylbenzyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-acetylbenzyl)benzamide(1039454-77-7)
• EPA Substance Registry System: N-(4-acetylbenzyl)benzamide(1039454-77-7)

Safety Data

• Hazardous Substances Data: 1039454-77-7(Hazardous Substances Data)

Upstream product

• 87171-25-3 1-[4-(aminomethyl)phenyl]ethan-1-one 
• 65-85-0 benzoic acid 
• 7441-43-2 4-ethylbenzylamine 
• 214759-42-9 1-[4-(aminomethyl)phenyl]-1-ethanol 
• 98-88-4 benzoyl chloride 
• 99-91-2 para-chloroacetophenone 

Downstream Products

• 1039454-20-0 ethyl 2-oxo-2-(4-{[(1-phenylmethanoyl)amino]methyl}phenyl)ethyl trithiocarbonate 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS USEFUL AS IDO AND/OR TDO MODULATORS

Present invention relates to novel heterocyclic compounds as indoleamine 2,3- dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) modulators. Compounds of the present invention inhibit tryptophan degradation by modulating IDO and/or TDO. Formula (I) The invention further relates to the process of their preparation, pharmaceutical composition and their use in modulating the activity of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3- dioxygenase (TDO). The compounds of the invention can be used alone or in combination for the treatment of conditions that benefits from the inhibition of tryptophan degradation.

Synthesis of amidomethyltrifluoroborates and their use in cross-coupling reactions

Amidomethyltrifluoroborates were successfully synthesized in a one-pot fashion and used in cross-coupling reactions with a wide variety of aryl and heteroaryl chlorides.