916213-93-9

Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl (3-cyanobenzyl)carbamate is used as a chemical intermediate for the synthesis of various drugs, contributing to the development of new pharmaceuticals with potential therapeutic benefits.
Used in Research and Development:
In the realm of research and development, tert-butyl (3-cyanobenzyl)carbamate serves as a building block for the creation of new molecules with potentially valuable properties, expanding the scope of chemical and pharmaceutical innovation.
Used in Insecticide Formulations:
Tert-butyl (3-cyanobenzyl)carbamate may be utilized as an active ingredient or component in insecticide formulations, providing effective pest control solutions in agriculture and other industries.
Used in Other Industrial Applications:
Beyond its pharmaceutical and pesticidal uses, tert-butyl (3-cyanobenzyl)carbamate may also find applications in other industries, capitalizing on its unique chemical properties for specific technical or manufacturing processes.

Upstream product

• 4248-19-5 tert-butyl carbazate 
• 24964-64-5 3-Cyanobenzaldehyde 
• 186581-53-3 diazomethane 
• 124-38-9 carbon dioxide 
• 1291065-70-7 N-(tert-butoxycarbonyl)-α-(phenylsulfonyl)-3-cyanobenzylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 40896-74-0 3-cyanobenzylamine hydrochloride 
• 557-21-1 dicyanozinc 
• 171663-13-1 t-butyl N-(3-bromobenzyl)carbamate 
• 328552-90-5 3-(azidomethyl)benzonitrile 
• 28188-41-2 m-(bromomethyl)benzonitrile 
• 10406-24-3 3-(aminomethyl)benzonitrile 

Downstream Products

• 1166832-07-0 tert-butyl {3-[amino(hydroxyimino)methyl]benzyl}carbamate 
• 10406-24-3 3-(aminomethyl)benzonitrile 
• 108467-99-8 1-(N-Boc-aminomethyl)-3-(aminomethyl)benzene 

Relevant academic research and scientific papers

One-pot synthesis of α-amino acids from CO2 using a bismetal reagent with Si-B bond

In the presence of 1.1 equiv of PhMe2Si-Bpin, 5 equiv of CsF, and 20 mol % of TsOH·H2O, precursors of N-Boc-imines can be converted into the corresponding α-aryl or α-alkenyl glycine derivatives under gaseous CO2 in moderate-to-high yields with a single operation. α-Isobutenyl glycine thus obtained can be further derivatized into various types of α-amino acids including N-Boc-leucine, serine, and glycine derivatives in short steps.

(3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING

The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. (Formula)

TRIAZOLE OXADIAZOLES DERIVATIVES

The invention relates to compounds of formula (I), wherein R1, R2, Ra, Rb, X have the meanings given in claim 1. The compounds are useful e.g. in the treatment of autoimmune disorders, such as multiple sclerosis.

Unexpected enhancement of thrombin inhibitor potency with o-aminoalkylbenzylamides in the P1 position

Thrombin inhibitors incorporating o-aminoalkylbenzylamides in the P1 position were designed, synthesized and found to have enhanced potency and selectivity in several different structural classes. X-ray crystallographic analysis of compound 24 bound in the α-thrombin-hirugen complex provides an explanation for these unanticipated results.