10424-29-0

Basic information

• Product Name: PHENYLSUCCINIC ACID
• Synonyms: phenylsuccinicacid96+%;Phenyl Succinic Aci
• CAS NO: 10424-29-0
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.184
• EINECS: 211-238-1
• Mol File: 10424-29-0.mol
• Article Data: 25

Chemical Properties

• Melting Point: 168°C
• Boiling Point: 290.62°C (rough estimate)
• Flash Point: 154.2°C
• Appearance: /
• Density: 1.2534 (rough estimate)
• Vapor Pressure: 0.000306mmHg at 25°C
• Refractive Index: 1.5430 (estimate)
• CAS DataBase Reference: PHENYLSUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLSUCCINIC ACID(10424-29-0)
• EPA Substance Registry System: PHENYLSUCCINIC ACID(10424-29-0)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S26:; S37/39:
• Hazardous Substances Data: 10424-29-0(Hazardous Substances Data)

Usage

General Description

Phenylsuccinic acid, also known as 2-phenylsuccinic acid, is a chemical compound with the molecular formula C10H10O4. It is a white crystalline solid that is insoluble in water and soluble in organic solvents. Phenylsuccinic acid is used in the synthesis of various pharmaceuticals and as an intermediate in the production of fragrances and flavoring compounds. It is also used as a building block for the preparation of polymers and resins. Phenylsuccinic acid has potential applications in the field of organic chemistry and materials science due to its versatile reactivity and structural properties. It is important to handle and store phenylsuccinic acid in a safe and controlled manner, as it may pose health and environmental hazards if not properly managed.

InChI:InChI=1/C10H10O4/c11-9(12)6-8(10(13)14)7-4-2-1-3-5-7/h1-5,8H,6H2,(H,11,12)(H,13,14)/p-2/t8-/m0/s1

Upstream product

• 14387-18-9 3-cyano-3-phenyl propionic acid 
• 4965-21-3 2-phenyl-ethane-1,1,2-tricarbonitrile 
• 108-31-6 maleic anhydride 
• 100-34-5 benzene diazonium chloride 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 493-72-1 5-phenyl-cyclohexane-1,3-dione 
• 74457-58-2 4-oxo-2-phenyl-butyric acid 
• 10035-10-6 hydrogen bromide 
• 64-19-7 acetic acid 
• 100727-23-9 2,4-dioxo-6-phenyl-cyclohexanecarbonitrile 
• 108262-44-8 3-Ethoxycarbonyl-2-phenyl-4-oxopentanenitrile 
• 90124-76-8 2-acetyl-3-phenyl-succinic acid diethyl ester 
• 408321-07-3 2,4-diphenyl-cyclopentane-1,3-dione 
• 41441-40-1 ethyl 3-phenyl-4-nitrobutanoate 

Downstream Products

• 15463-92-0 dimethyl 2-phenylsuccinate 
• 15463-92-0 (S)-(+)-dimethyl 2-phenylsuccinate 
• 150508-16-0 3-phenyl-1-propyl-pyrrolidine-2,5-dione 
• 2321-07-5 fluorescein 
• 34861-81-9 diethyl phenylsuccinate 
• 36122-35-7 2-phenylmaleic anhydride 
• 30952-65-9 2-hydroxy-2-phenylbutanedioic acid 
• 29427-69-8 3-oxoindan-1-carboxylic acid 
• 32676-72-5 phenylsuccinyl chloride 
• 21021-53-4 4-Nitrophenylsuccinic acid 
• 6332-94-1 (2-nitro-phenyl)-succinic acid 
• 1131-15-3 2-phenylsuccinic anhydride 
• 98132-80-0 1-(2-diethylamino-ethyl)-3-phenyl-pyrrolidine-2,5-dione 
• 54433-51-1 1-allyl-3-phenyl-pyrrolidine-2,5-dione 

Related news

Efficient enantioseparation of PHENYLSUCCINIC ACID (cas 10424-29-0) enantiomers by aqueous two-phase system-based biphasic recognition chiral extraction: Phase behaviors and distribution experiments08/07/2019

A novel method of aqueous two-phase system (ATPS)-based biphasic recognition chiral extraction has been developed to separate phenylsuccinic acid (PSA) enantiomers. The phase behaviors of ethanol/ammonium sulfate ATPS including phase diagrams, phase volume ratios and phase compositions were stud...detailed

Enantioselective extraction of PHENYLSUCCINIC ACID (cas 10424-29-0) in aqueous two-phase systems based on acetone and β-cyclodextrin derivative: Modeling and optimization through response surface methodology08/05/2019

A novel aqueous two-phase system (ATPS) composed of β-cyclodextrin (β-CD) derivative and acetone was developed for enantioselective extraction of racemic phenylsuccinic acid (PSA). Binodal curves, tie-lines, and critical points for the investigated ATPS were determined and the experimental tie...detailed

Enantioseparation of PHENYLSUCCINIC ACID (cas 10424-29-0) by high speed counter-current chromatography using hydroxypropyl-β-cyclodextrin as chiral selector08/04/2019

High speed counter-current chromatography (HSCCC) was successfully applied to resolution of phenylsuccinic acid (PSA) with hydroxypropyl-β-cyclodextrin (HP-β-CD) as chiral selector (CS). The two-phase solvent system composed of n-hexane–methyl tert-butyl ether–0.1 mol L−1 phosphate buffer so...detailed

Equilibrium Studies on Liquid-Liquid Reactive Extraction of PHENYLSUCCINIC ACID (cas 10424-29-0) Enantiomers Using Hydrophilic β-CD Derivatives Extractants07/31/2019

This paper deals with the enantioseparation of phenylsuccinic acid (H2A) enantiomers by liquid-liquid reactive extraction using β-CD derivatives as aqueous selectors. Cyclodextrin and its derivatives can interact with guest molecules selectively to form complexes with different stabilities. Cyc...detailed

Relevant articles and documents

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Enamines; 45. A New Simple Synthesis of 2-Phenylsuccinic Acids

A simple route to 2-phenylsuccinic acids consists of the reaction of 1,1-dimorpholinoethene with β-nitrostyrenes at room temperature and hydrolysis of the 1:1 adduct thus obtained with hydrochloric acid.The method affords good overall yields of 2-phenylsuccinic acids.

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Photoredox Activation of Formate Salts: Hydrocarboxylation of Alkenes via Carboxyl Group Transfer

A photoredox activation mode of formate salts for carboxylation was developed. Using a formate salt as the reductant, carbonyl source, and hydrogen atom transfer reagent, a wide range of alkenes can be converted into acid products via a carboxyl group tra

Stereoselective One-Pot Synthesis of cis-1,2-Dicyanoalkenes from 1,1-Bis(benzenesulfonyl)alkenes and KCN

An efficient synthesis of cis-1,2-dicyanoalkenes by the reaction of 1,1-bis(benzenesulfonyl)alkenes with KCN was developed. This reaction was conducted in the presence of tetrabutylammonium bromide and NH4Cl/K3PO4 under phase-transfer conditions. A series of cis-1,2-dicyanoalkenes were obtained in good to high yields. Further transformation of the obtained product allows for access to imide and dicarboxylic acid compounds.