1042977-36-5Relevant academic research and scientific papers
Tunable Aerobic Oxidative Hydroxylation/Dehydrogenative Homocoupling of Pyrazol-5-ones under Transition-Metal-Free Conditions
Sheng, Xuguang,Zhang, Jinlong,Yang, Huameng,Jiang, Gaoxi
supporting information, p. 2618 - 2621 (2017/05/24)
A practical and tunable transition-metal-free aerobic oxidation of pyrazol-5-ones preparing either 4-hydroxypyrazoles (via C-H hydroxylation) or bispyrazoles (via dehydrogenative homocoupling) is described. The K2CO3/dioxane reagent system predominately promoted hydroxylation to deliver the α-hydroxylated pyrazoles. In contrast, the formation of bispyrazoles was overwhelmingly preferred with CH3CN as the reaction medium without any additives.
Superoxide catalyzed oxidation of 4-alkylsubstituted pyrazol-5-ones to 4-alkyl-4-hydroxysubstituted pyrazol-5-ones
Singh, Sundaram,Singh, Satish Kumar,Singh, Krishna Nand
, p. 825 - 827 (2008/12/21)
Superoxide ion, generated in situ by the phase transfer reaction of potassium superoxide and tetraethylammonium bromide, brings about an easy oxidation of different 4-alkylsubstituted pyrazol-5-ones to yield 4-alkyl-4-hydroxy pyrazol-5-ones in reasonably
