104307-08-6Relevant articles and documents
Formal total synthesis of okadaic acid via regiocontrolled gold(I)-catalyzed spiroketalizations
Fang, Chao,Pang, Yucheng,Forsyth, Craig J.
supporting information; experimental part, p. 4528 - 4531 (2010/12/18)
Both C19 and C34 spiroketal domains of okadaic acid were assembled using gold(I) chloride catalyzed spiroketalizations, and the two resulting fragments were coupled to give the C15 - C38 fragment of okadaic acid, a known intermediate for the total synthesis of this important natural product.
SYNTHETIC STUDIES TOWARD MARINE TOXIC POLYETHERS THE TOTAL SYNTHESIS OF OKADAIC ACID
Isobe, Minoru,Ichikawa, Yoshiyasu,Goto, Toshio
, p. 963 - 966 (2007/10/02)
The total synthesis of okadaic acid has been accomplished through the coupling of all the segments, A, B and C, by means of sulfone-carbanion strategy.