104664-93-9Relevant articles and documents
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Beckwith,A.J.,Zavitsas,A.A.
, p. 8230 (1986)
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METHOD OF CONVERTING ALCOHOL TO HALIDE
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Page/Page column 53; 110, (2017/01/02)
The present invention relates to a method of converting an alcohol into a corresponding halide. This method comprises reacting the alcohol with an optionally substituted aromatic carboxylic acid halide in presence of an N-substituted formamide to replace a hydroxyl group of the alcohol by a halogen atom. The present invention also relates to a method of converting an alcohol into a corresponding substitution product. The second method comprises: (a) performing the method of the invention of converting an alcohol into the corresponding halide; and (b) reacting the corresponding halide with a nucleophile to convert the halide into the nucleophilic substitution product.
Novel reactivity of stabilized methylenetributylphosphorane: A new mitsunobu reagent
Tsunoda, Tetsuto,Ozaki, Fumie,Ito, Sho
, p. 5081 - 5082 (2007/10/02)
Cyanomethylenetributylphosphorane was shown to mediate the direct condensation of alcohols with O- and N-nucleophiles. A secondary alcohol, 2- octanol, reacted satisfactorily with Walden inversion of its carbinyl carbon.