104750-47-2

Upstream product

• 554-12-1 propanoic acid methyl ester 
• 57768-35-1 1-(phenylthio)-1-cyclohexanecarboxaldehyde 
• 931-59-9 benzenesulfenyl chloride 
• 2043-61-0 cyclohexanecarbaldehyde 
• 53282-55-6 (trimethylsiloxymethylidene)cyclohexane 

Downstream Products

• 104750-58-5 (1RS,2'RS)-(E)-2-<3'-(t-butyldiphenylsiloxy)-2'-methylpropylidene>cyclohexyl 3,5-dinitrobenzoate 
• 104750-58-5 (1RS,2'SR)-(E)-<3'-(t-butyldiphenylsiloxy)-2'-methylpropylidene>cyclohexyl 3,5-dinitrobenzoate 
• 104750-45-0 (3-Benzenesulfinyl-3-cyclohex-1-enyl-2-methyl-propoxy)-tert-butyl-diphenyl-silane 
• 104750-44-9 (1'RS,2'SR)-1-<3'-(t-butyldiphenylsiloxy)-2'-methyl-1'-(phenylthio)propyl>cyclohexene 
• 104750-43-8 (1RS,2RS)-3-(t-butyldiphenylsiloxy)-2-methyl-1-<1-(phenylthio)cyclohexyl>propan-1-ol 
• 104750-46-1 <1RS,2'SR>-(E)-2-<3'-(t-butyldiphenylsiloxy)-2'-methylpropylidene>cyclohexanol 
• 85287-85-0 (3RS,4RS)-3-methyl-4-phenylthio-1-oxaspiro<4,5>decan-2-one 
• 104750-42-7 (3RS,4SR)-3-methyl-4-phenylthio-1-oxaspiro<4.5>decane 
• 133030-76-9 (1RS,2'RS)-(E)-2-(3'-hydroxy-2'-methylpropylidene)cyclohexanol 
• 104750-45-0 ((2S,3S)-3-Benzenesulfinyl-3-cyclohex-1-enyl-2-methyl-propoxy)-tert-butyl-diphenyl-silane 
• 104750-44-9 (1'RS,2'RS)-1-<3'-(t-butyldiphenylsiloxy)-2'-methyl-1'-(phenylthio)propyl>cyclohexene 
• 104750-43-8 (1RS,2SR)-3-(t-butyldiphenylsiloxy)-2-methyl-1-<1-(phenylthio)cyclohexyl>propan-1-ol 
• 104750-46-1 (1RS,2'RS)-2-<3'-(t-butyldiphenylsiloxy)-2'-methylpropylidene>cyclohexanol 
• 104750-42-7 (3RS,4RS)-3-methyl-4-phenylthio-1-oxaspiro<4.5>decane 

Relevant academic research and scientific papers

Stereoselective substituted pyrrolidine and cyclic ether synthesis by PhS migration

The effect of substitution on heterocycle synthesis by a novel silica gel catalysed decarboxylative ring-closing reaction is shown to be stereospecific and dependent on the nature of the nitrogen substituent.

Synthesis of Cyclic Amines and Allylic Sulfides by Phenylthio Migration of β-Hydroxy Sulfides

Rearrangement of β-hydroxy sulfides proceeds stereospecifically with capture of the episulfonium ion by the nitrogen atom of an amide.Almost quantitative yields of substituted pyrrolidines are obtained using a sulfonamide as the intramolecular nucleophile

Transformation of Cyclic α-Phenylthio Aldehydes by Stereoselective Aldol Reactions and Phenylthio Migration into Spirocyclic Lactones and Ethers, and E-Allylic Alcohols with 1,4-Related Chiral Centres

syn- and anti-Selective aldol reactions between enolates of propionate esters and three α-phenylthio cycloalkanecarbaldehydes give single diastereoisomers of phenylthio alcohols which rearrange in acid with 5-hydroxy or 5-CO2H participation to give spiroc

PHENYLTHIO(PhS) MIGRATION IN THE STEREOCONTROLLED SYNTHESIS OF ALLYLIC ALCOHOLS WITH 1,4 RELATED CHIRAL CENTRES.

Stereoselective aldol products are transformed by PhS migration into lactones, tetrahydrofurans, and, by subsequent Evans-Mislow rearrangement, into the title compounds with complete stereochemical control.