10503-37-4Relevant academic research and scientific papers
Observations on the generation of organozinc carbenoids from acetals and ketals
Motherwell, William B.,O'Mahony, Donogh J.R.,Popkin, Matthew E.
, p. 5285 - 5288 (1998)
The use of acetals and ketals as direct precursors for organozinc carbenoid chemistry is illustrated by their direct conversion to alkenes in a one pot operation. Aryl acetals can also be used as precursors for the cyclopropanation of cyclohexene.
Gold Sulfonium Benzylide Complexes Undergo Efficient Benzylidene Transfer to Alkenes
Carden, Robert G.,Widenhoefer, Ross A.
supporting information, p. 11026 - 11030 (2019/08/12)
The gold sulfonium benzylide complexes [(P1)AuCHPh(SR1R2)]+ {B[3,5-CF3C6H3]4}? [P1=P(tBu)2o-biphenyl; R1, R2=-(CH2)4- (1 a); R1=Et, R2=Ph (1 b); R1=R2=Ph (1 c)] were synthesized by reaction of the gold α-chloro benzyl complex (P1)AuCHClPh with sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate and excess sulfide. Complexes 1 undergo efficient benzylidene transfer to alkenes and DMSO under mild conditions without external activation. Kinetic analysis of the reaction of 1 c with styrene was consistent with the intermediacy of the cationic gold benzylidene complex [(P1)AuCHPh]+ (I).
A Practical Cyclopropanation Method using Direct Generation of Organozinc Carbenoids from Carbonyl Compounds
Motherwell, William B.,Roberts, Lee R.
, p. 1582 - 1583 (2007/10/02)
A variety of readily available aryl and α,β-unsaturated carbonyl compounds, on treatment with zinc and 1,2-bis(chlorodimethylsilyl)ethane, afforded organozinc carbenoids which may be trapped with alkenes to give cyclopropanes.
