10504-96-8

Basic information

• Product Name: N-[(4-bromophenyl)methyl]-4-methylbenzenesulfonamide
• Synonyms: N-[(4-bromophenyl)methyl]-4-methylbenzenesulfonamide
• CAS NO: 10504-96-8
• Molecular Weight: 340.241
• Mol File: 10504-96-8.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: N-[(4-bromophenyl)methyl]-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(4-bromophenyl)methyl]-4-methylbenzenesulfonamide(10504-96-8)
• EPA Substance Registry System: N-[(4-bromophenyl)methyl]-4-methylbenzenesulfonamide(10504-96-8)

Safety Data

• Hazardous Substances Data: 10504-96-8(Hazardous Substances Data)

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 873-75-6 4-bromobenzenemethanol 
• 70-55-3 toluene-4-sulfonamide 
• 106-38-7 para-bromotoluene 
• 29281-83-2 4-methylbenzensulphonamide potassium salt 
• 3959-07-7 4-Bromobenzylamine 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 106-45-6 para-thiocresol 
• 941-55-9 4-toluenesulfonyl azide 
• 254428-47-2 (E)-N-(4-bromobenzylidene)-4-methylbenzenesulfonamide 
• 1122-91-4 4-bromo-benzaldehyde 
• 13150-76-0 N-[(4-methylphenyl)sulfonyl]-S,S-diphenyl-sulfilimine 
• 98-59-9 p-toluenesulfonyl chloride 
• 36176-90-6 N-(4-bromobenzylidene)-4-methylbenzenesulfonamide 

Downstream Products

• 53039-48-8 1-(4-bromobenzyl)-4-methoxybenzene 
• 1333226-10-0 N,N-ditosyl-4-bromobenzylamine 
• 1527501-90-1 N-(1-acetyl-1H-indol-2-yl)-N-(4-bromobenzyl)-4-methylbenzenesulfonamide 
• 1527501-74-1 N-(4-bromobenzyl)-N-(1H-indol-2-yl)-4-methylbenzenesulfonamide 
• 1527501-77-4 N-(5-bromo-1H-indol-2-yl)-N-(4-bromobenzyl)-4-methylbenzenesulfonamide 
• 36176-90-6 N-(4-bromobenzylidene)-4-methylbenzenesulfonamide 

Relevant articles and documents

Synthesis of sulfonamides via I2-mediated reaction of sodium sulfinates with amines in an aqueous medium at room temperature

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Nickel/Photoredox Dual Catalytic Cross-Coupling of Alkyl and Amidyl Radicals to Construct C(sp3)-N Bonds

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Yndiamides (bis-N-substituted alkynes) are valuable precursors to azacycles. Here we report a cycloisomerization/1,2-sulfonyl migration of alkynyl-yndiamides to form tetrahydropyrrolopyrroles, unprecedented heterocyclic scaffolds that are relevant to medicinal chemistry. This functional group tolerant transformation can be achieved using Au(I) catalysis that proceeds at ambient temperature, and a thermally promoted process. The utility of the products is demonstrated by a range of reactions to functionalize the fused pyrrole core.

Method for synthesizing N-alkyl sulfonamide in water

The invention discloses a method for synthesizing N-alkyl sulfonamide in water, in particular to a method for synthesizing an N-alkyl sulfonamide derivative from a sulfonamide derivative and alcohol,and a water-soluble iridium complex is adopted to catalyze the reaction of N-alkyl sulfonamide. Compared with the previous synthesis method, the method has the advantages that a reaction equivalent substrate is used in the reaction process, so that raw material waste is avoided; weak base is used, and reaction conditions are mild; non-toxic and harmless pure water is used as a solvent in the reaction, only water is generated as a by-product, the atom reaction economy is high, and the requirement of green chemistry is met.