106248-72-0Relevant academic research and scientific papers
The Use of a Mannitol-Derived Fused Oxacycle as a Combinatorial Scaffold
Timmer, Mattie S. M.,Verdoes, Martijn,Sliedregt, Leo A. J. M.,Van Der Marel, Gijsbert A.,Van Boom, Jacques H.,Overkleeft, Herman S.
, p. 9406 - 9411 (2007/10/03)
An efficient and high-yielding solid-phase synthesis of a small library of compounds containing a cis-fused pyranofuran structural motive is descibed. With use of the cheap and readily available D-(+)-mannitol, a highly functionalized sugar template was synthesized and immobilized on a solid support via an olefinic linker. Modification of this two-point molecular scaffold and subsequent ring-closing metathesis/cleavage gave access to a series of functionalized conformationally constrained fused oxacycles.
Mono- and Dioxetanes of 2,5-Anhydroalditols, Syntheses and Reactions
Koell, Peter,Oelting, Michael
, p. 205 - 214 (2007/10/02)
Starting from appropriate 2,5-anhydroalditols the monooxetanes 3, 9, 15, and 20 have been prepared by selective monotosylation of primary hydroxy groups and subsequent treatment with base.Analogous reactions gave the 1,3:2,5:4,6-trianhydrohexitols 10 and
