106331-72-0

Basic information

• Product Name: Pyridine, 3-bromo-2,5,6-trimethoxy-
• CAS NO: 106331-72-0
• Molecular Formula: C8H10BrNO3
• Mol File: 106331-72-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyridine, 3-bromo-2,5,6-trimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-bromo-2,5,6-trimethoxy-(106331-72-0)
• EPA Substance Registry System: Pyridine, 3-bromo-2,5,6-trimethoxy-(106331-72-0)

Safety Data

• Hazardous Substances Data: 106331-72-0(Hazardous Substances Data)

Upstream product

• 52605-97-7 2,3-dimethoxypyridine 
• 52605-96-6 2-chloro-3-methoxypyridine 
• 106331-71-9 5,6-dibromo-2,3-dimethoxypyridine 
• 124-41-4 sodium methylate 
• 6636-78-8 2-chloro-3-hydroxypyridine 

Downstream Products

• 1364917-20-3 2,5,6-trimethoxynicotinic acid 

Relevant articles and documents

Synthetic method of 2,5,6-trimethoxy-3-picolinic acid

The invention relates to a synthetic method of 2,5,6-trimethoxy-3-picolinic acid, which mainly solves the technical problem that no effective synthetic methods are provided at present. The synthetic method provided by the invention comprises the following steps: converting 2-chloro-3-hydroxypyridine hydroxy into methoxy; carrying out methoxy nucleophilic substitution of chlorine; carrying out bromination of a pyridine ring; and carrying out methoxy selective substitution of bromine; removing bromine from n-butyllithium, reacting with carbon dioxide, and introducing carboxy so as to obtain 2,5,6-trimethoxy-3-picolinic acid. In the whole synthetic process, intermediates and object products do not need to be separated through a chromatographic column, the raw materials are cheap, and the purification is simple.