1067883-80-0

Basic information

• Product Name: N-methyl-2-(2'-bromophenyl)-1H-indole
• Synonyms: N-methyl-2-(2'-bromophenyl)-1H-indole
• CAS NO: 1067883-80-0
• Molecular Weight: 286.171
• Mol File: 1067883-80-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: N-methyl-2-(2'-bromophenyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-2-(2'-bromophenyl)-1H-indole(1067883-80-0)
• EPA Substance Registry System: N-methyl-2-(2'-bromophenyl)-1H-indole(1067883-80-0)

Safety Data

• Hazardous Substances Data: 1067883-80-0(Hazardous Substances Data)

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 618-40-6 1-Methyl-1-phenylhydrazine 
• 88207-45-8 2-(2'-bromophenyl)-1H-indole 
• 74-88-4 methyl iodide 
• 100-63-0 phenylhydrazine 
• 622-36-6 1-methyl-2-phenylhydrazine 
• 1011736-72-3 N-[1-(2-Bromo-phenyl)-eth-(Z)-ylidene]-N'-phenyl-hydrazine 
• 603-76-9 1-methylindole 
• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 583-55-1 1-Bromo-2-iodobenzene 

Downstream Products

• 1067883-59-3 N-methyl-2-[2-(diisopropylphosphino)phenyl]-1H-indole 
• 1067883-56-0 N-methyl-2-[2-(diphenylphosphino)phenyl]-1H-indole 
• 1067883-58-2 2-[2-(dicyclohexylphosphino)-phenyl]-1-methyl-1H-indole 
• 1225381-24-7 2-(2-[1-(tert-butyl)-1-chlorophosphino]phenyl)-1-methyl-1H-indole 
• 1263875-75-7 5,6-dibutyl-11-methyl-11-H-benzo[a]carbazole 

Relevant articles and documents

Direct Copper-Catalyzed C-3 Arylation of Diphenylphosphine Oxide Indoles

We have developed a simple and effective method for the C-3 arylation of phosphorus-containing indole compounds in the presence of CuI under mild conditions. This reaction provides a reliable method for the modification of ligands.

NaNO2/K2S2O8-mediated Selective Radical Nitration/Nitrosation of Indoles: Efficient Approach to 3-Nitro- and 3-Nitrosoindoles

JPZ acknowledges financial support from the National Natural Science Foundation of China (No. 21172163, 21472133), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), and Key Laboratory of Organic Synthesis of Jiangsu Province (KJS1749). (Figure presented.).

Syntheses of Tetrahydrobenzoazepinoindoles and Dihydrobenzodiazepinoindoles via Ring-Opening Cyclization of Activated Aziridines with 2-(2-Bromophenyl)-1H-indoles

Two efficient, modular, step- and pot-economic strategies to access various 5,6,7,12-tetrahydrobenzo[2,3]azepino[4,5-b]indoles and 6,7-dihydro-5H-benzo[5,6][1,4]diazepino[1,7-a]indoles are disclosed that advance via SN2-type regioselective ring opening of enantiopure aziridines with 2-(2-bromophenyl)-1H-indoles at their C3 and indolyl N centers, respectively, followed by Cu-mediated C-N cyclization which furnishes the products in excellent yields with outstanding enantiomeric excesses (up to >99%).