106791-94-0

Basic information

• Product Name: 2-amino-5-fluoro-6-phenylpyrimidin-4(1H)-one
• CAS NO: 106791-94-0
• Molecular Formula: C₁₀H₈FN₃O
• Molecular Weight: 205.1884
• Mol File: 106791-94-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 345.3°C at 760 mmHg
• Flash Point: 162.6°C
• Density: 1.43g/cm³
• Vapor Pressure: 6.23E-05mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: 2-amino-5-fluoro-6-phenylpyrimidin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-5-fluoro-6-phenylpyrimidin-4(1H)-one(106791-94-0)
• EPA Substance Registry System: 2-amino-5-fluoro-6-phenylpyrimidin-4(1H)-one(106791-94-0)

Safety Data

• Hazardous Substances Data: 106791-94-0(Hazardous Substances Data)

Upstream product

• 28383-65-5 ethyl 2-diazo-3-oxo-3-phenylpropanoate 
• 1479-22-7 ethyl 2-fluoro-3-oxo-3-phenylpropionate 
• 593-85-1 diguanidine carbonate 
• 76435-47-7 methyl 2-fluoro-3-oxo-3-phenylpropionate 
• 113-00-8 guanidine nitrate 
• 93-58-3 benzoic acid methyl ester 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 

Relevant articles and documents

Synthesis of 6-arylisocytosines and their potential for hydrogen bonding interactions

Abstract The synthesis of a number of 6-arylisocytosines, including linked bis-isocytosines, from the reaction of guanidine with β-ketoesters is described. The compounds were investigated for their ability to form hydrogen-bonded structural networks, and for their potential interactions with the telomeric quadruplex forming sequence AGGG(TTAGGG)3.

4-substituted-6-aryl-pyrimidine compounds

This invention describes the synthesis and anti-neoplastic use of 4-aziridyl-5-substituted/unsubstituted 6-aryl-pyrimidine compounds of Formula IA STR1 as well as N'-[2-(1-aziridyl)ethyl]-6-aryl-2,4-pyrimidinediamines of Formula IB STR2 and 4-chloro or bromo-5-substituted/unstubstituted-6-aryl-pyrimidines.