1075-11-2

Basic information

• Product Name: 6-FLUOROISOQUINOLINE
• Synonyms: 6-FLUOROISOQUINOLINE
• CAS NO: 1075-11-2
• Molecular Formula: C₉H₆FN
• Molecular Weight: 147.15
• Mol File: 1075-11-2.mol
• Article Data: 11

Chemical Properties

• Melting Point: 48-50℃
• Boiling Point: 255.265 °C at 760 mmHg
• Flash Point: 108.181 °C
• Appearance: /
• Density: 1.216 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.27±0.10(Predicted)
• CAS DataBase Reference: 6-FLUOROISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-FLUOROISOQUINOLINE(1075-11-2)
• EPA Substance Registry System: 6-FLUOROISOQUINOLINE(1075-11-2)

Safety Data

• Hazardous Substances Data: 1075-11-2(Hazardous Substances Data)

Usage

General Description

6-Fluoroisoquinoline is a chemical compound with the molecular formula C9H6FN. It is a fluorinated derivative of isoquinoline, which is commonly used as a building block in the synthesis of biologically active compounds and pharmaceuticals. 6-Fluoroisoquinoline has a wide range of applications and is often used as a precursor in the production of various drugs and agrochemicals. It is also used in research and development to create new molecules with potential therapeutic benefits. Additionally, 6-Fluoroisoquinoline is utilized as a fluorescent probe in analytical chemistry and bioimaging studies. However, it is important to handle this compound with care as it is toxic and potentially harmful if ingested or inhaled.

Upstream product

• 700-84-5 5-fluoro-1-indanone 
• 52163-88-9 6-fluoro-1H-indene 
• 52085-92-4 5-fluoro-2,3-dihydro-1H-inden-1-ol 
• 7651-82-3 isoquinolin-6-ol 
• 34784-05-9 6-bromo-isoquinoline 
• 918488-54-7 N-(2,2-dimethoxy-ethyl)-N-(4-fluoro-benzyl)-4-methyl-benzene-sulfonamide 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 214045-85-9 6-fluoro-1,2-dihydroisoquinolin-1-one 
• 608515-77-1 6-fluoro-1-methylisoquinoline 
• 119-65-3 isoquinoline 
• 214045-86-0 1-chloro-6-fluoroisoquinoline 
• 1416500-78-1 4-bromo-6-fluoro-isoquinoline 
• 1239463-43-4 5-bromo-6-fluoroisoquinoline 

Relevant articles and documents

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PhenoFluor: Practical synthesis, new formulation, and deoxyfluorination of heteroaromatics

We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.

CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLONE DERIVATIVES

The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and composit