107504-07-4

Basic information

• Product Name: 2-Pyridinecarboxylicacid,5-fluoro-,methylester(9CI)
• Synonyms: 2-Pyridinecarboxylicacid,5-fluoro-,methylester(9CI);5-Fluoropyridine-2-carboxylic acid methyl ester;Methyl 5-fluoropicolinate;Methyl 5-fluoropyridine-2-carboxylate;2-PYRIDINECARBOXYLIC ACID, 5-FLUORO-, METHYL ESTER;5-fluoro-2-pyridinecarboxylic acid methyl ester
• CAS NO: 107504-07-4
• Molecular Formula: C₇H₆FNO₂
• Molecular Weight: 155.13
• Product Categories: HALIDE
• Mol File: 107504-07-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 217.2°C at 760 mmHg
• Flash Point: 85.1°C
• Appearance: /
• Density: 1.243g/cm³
• Vapor Pressure: 0.135mmHg at 25°C
• Refractive Index: 1.49
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -0.73±0.10(Predicted)
• CAS DataBase Reference: 2-Pyridinecarboxylicacid,5-fluoro-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxylicacid,5-fluoro-,methylester(9CI)(107504-07-4)
• EPA Substance Registry System: 2-Pyridinecarboxylicacid,5-fluoro-,methylester(9CI)(107504-07-4)

Safety Data

• Hazardous Substances Data: 107504-07-4(Hazardous Substances Data)

Usage

General Description

2-Pyridinecarboxylic acid, 5-fluoro-, methylester (9CI) is a chemical compound with the molecular formula C7H6FNO2. It is a methyl ester derivative of 5-fluoro-2-pyridinecarboxylic acid, a heterocyclic compound with potential biological activity. This chemical may have applications in the pharmaceutical and agrochemical industries, as well as in research and development. It is important to handle this chemical with care, as it may have potential hazards and should be used in accordance with proper safety procedures and guidelines.

InChI:InChI=1/C7H6FNO2/c1-11-7(10)6-3-2-5(8)4-9-6/h2-4H,1H3

Upstream product

• 29682-15-3 methyl 5-bromopicolinate 
• 67515-76-8 methyl 5-amino-2-pyridinecarboxylate 
• 29682-14-2 5-nitro-pyridine-2-carboxylic acid methyl ester 
• 132308-19-1 methyl 5-chloropyridine-2-carboxylate 
• 107504-08-5 5-fluoropicolinic acid 
• 67-56-1 methanol 

Downstream Products

• 860296-24-8 6-chloro-5-fluoro-pyridine-2-carboxylic acid 
• 1214337-05-9 6-chloro-5-fluoro-2-picolinic acid methyl ester 
• 31181-88-1 5-fluoropicolinaldehyde 
• 802325-29-7 5-fluoro-2-hydroxylmethylpyridine 

Relevant articles and documents

ASK1 inhibitor and application thereof

The invention relates to compounds represented by a general formula (I) shown in the specification, a pharmaceutically acceptable salt and ester, or a stereoisomer of the compounds. The invention alsorelates to a preparation method of the compounds, a pharmaceutical preparation and a pharmaceutical composition containing the compounds. The compounds provided by the invention can effectively inhibit the amino acid phosphorylation of ASK1 and inhibit the activation of the ASK1; therefore, the compounds can treat and/or prevent ASK1-mediated diseases and related diseases.

NOVEL INDOLIZINE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds.

PROCESS FOR FLUORINATING COMPOUNDS

Methods of preparing a fluorinated aryl or heteroaryl substrate by combining a quaternary ammonium cyanide and an aryl or heteroaryl substrate substituted with at least one chloro, bromo, sulfonyl, or nitro group to thereby provide a mixture, and combining the mixture with hexafluorobenzene to thereby provide the fluorinated substrate.