108-14-5

Basic information

• Product Name: 2-chloropropyldimethylamine
• Synonyms: 2-chloropropyldimethylamine;2-CHLORO-N,N-DIMETHYL-1-PROPYLAMINE;2-Chloro-1-dimethylaminopropane;2-chloro-n,n-dimethyl propylamine;2-Chloro-N,N-dimethyl-1-propanamine;2-Chloro-N,N-dimethylpropan-1-amine;1-Propanamine, 2-chloro-N,N-dimethyl- (9ci);Einecs 203-554-3
• CAS NO: 108-14-5
• Molecular Formula: C5H12ClN
• Molecular Weight: 121.60848
• EINECS: 203-554-3
• Mol File: 108-14-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 81.1°Cat760mmHg
• Flash Point: 2.9°C
• Appearance: /
• Density: 0.934g/cm³
• Vapor Pressure: 83mmHg at 25°C
• Refractive Index: 1.432
• PKA: 8.56±0.28(Predicted)
• CAS DataBase Reference: 2-chloropropyldimethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloropropyldimethylamine(108-14-5)
• EPA Substance Registry System: 2-chloropropyldimethylamine(108-14-5)

Safety Data

• Hazardous Substances Data: 108-14-5(Hazardous Substances Data)

Usage

General Description

2-chloropropyldimethylamine is an organic compound with the chemical formula C5H12ClN. It is a clear, colorless liquid with a strong ammonia-like odor. This chemical is widely used as an intermediate for the production of agricultural chemicals, dyes, and pharmaceuticals. It is also utilized as a corrosion inhibitor, emulsifying agent, and as a raw material for the synthesis of quaternary ammonium compounds. Additionally, 2-chloropropyldimethylamine is commonly employed in the synthesis of surfactants and as a chemical intermediate in the production of specialty chemicals. It is important to handle this chemical with care, as it is classified as a hazardous substance and can cause skin and eye irritation, as well as respiratory issues if inhaled.

InChI:InChI=1/C5H12ClN/c1-5(6)4-7(2)3/h5H,4H2,1-3H3

Upstream product

• 56-23-5 tetrachloromethane 
• 108-16-7 1-methyl-2-N,N-dimethylaminoethanol 
• 53309-35-6 (2-chloro-1-methyl-ethyl)-dimethyl-amine 
• 926-63-6 N,N-dimethylaminopropane 
• 67-66-3 chloroform 
• 7782-50-5 chlorine 
• 4584-49-0 (2-chloropropyl)dimethylamine hydrochloride 
• 15521-18-3 2-(dimethylamino)propan-1-ol 

Downstream Products

• 60-87-7 10-[2-(dimethylamino)propyl]phenothiazine 
• 303-14-0 isopromethazine 
• 604-73-9 Chlorpromazin 
• 54742-82-4 3-(2-dimethylamino-1-methyl-ethyl)-5,5-diphenyl-imidazolidine-2,4-dione 
• 412033-15-9 1,3-dimethyl-4-phenyl-hexahydro-azepine-4-carbonitrile 
• 5844-21-3 benzoic acid-[N'-(β-dimethylamino-isopropyl)-hydrazide] 
• 92043-41-9 dimethyl-[2-(2-[1,3,4]oxadiazol-2-yl-phenoxy)-propyl]-amine 
• 3705-00-8 2'-(2-Dimethylamino-1-methyl-aethoxy)-4'-methyl-acetophenon 
• 94911-53-2 [4-(2-Dimethylamino-1-methyl-ethoxy)-3,5-dimethyl-phenyl]-phenyl-methanone 
• 3704-98-1 3'-(2-Dimethylamino-1-methyl-ethoxy)-acetophenon 
• 3705-05-3 4'-<2-Dimethylamino-1-methyl-aethoxy>-butyrophenon 
• 3950-36-5 3-Chlor-4-<2-dimethylamino-1-methyl-aethoxy>-benzophenon 
• 14715-14-1 [2-(2-Benzyl-3H-inden-1-yl)-propyl]-dimethyl-amine 
• 18708-06-0 1-Phenyl-3,5-dimethylcyclohexyl-(1)-<(2-dimethylamino-1-methyl)-ethyl>-ether 

Relevant articles and documents

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COMPOSITIONS AND METHODS FOR THE TREATMENT OF SEVERE PAIN

The invention relates to the compounds of formula (I) or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula (I), and methods for the treatment of severe pain may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of chronic pain, generalized pain disorders, leukemia, cancer, chronic pain, chemotherapy induced pain, epilepsy, migraine, neuropathic pain, post herpetic neuralgia, neuralgia, pain, drug addiction, detoxification of drugs, Alzheimer's disease, multiple sclerosis, multiple sclerosis restless legs syndrome (RLS), cluster headache, depression, fibromyalgia, amyotrophic lateral sclerosis (ALS), convulsions, partial seizures, mood-stabilizing agent and bipolar disorder.

PHENOTHIAZINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Phenothiazine derivatives of formula: STR1 in which Y is hydrogen or halogen, R 1 and R 2, which may be identical or different, denote alkyl, cycloalkyl-alkyl, hydroxyalkyl or acetyloxyalkyl radicals or form, together with the nitrogen atom to which they are attached, an optionally substituted, saturated or partially unsaturated 4-to 7-membered heterocycle; and either X is oxygen, sulphur or: N-R 4, R is cycloalkyl, phenyl or--CH 2 R 3, R 3 is H, alkyl (1 to 5 C), alkenyl or alkynyl (2 to 4 C), cycloalkyl (3 to 6 C), phenyl, substituted phenyl or a heterocyclic radical, R 4 is H or--CN, except that X is not oxygen if, simultaneously, R 3 is H or alkyl, R. sub.1 and R 2 are alkyl or NR 1 R 2 forms an unsubstituted heterocycle, and Y is H; or X is: N-R 4 and R 4 forms, with R and the neighbouring atoms, an optionally substituted imidazolyl or imidazolinyl radical or a hexahydrobenzimidazolyl radical, in their isomeric forms and mixtures thereof and their acid addition salts are useful as analgesics and diuretics.