108082-72-0

Basic information

• Product Name: 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE
• Synonyms: 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE;PYRIDINE,2-CHLORO-3-(PHENYLMETHOXY)-
• CAS NO: 108082-72-0
• Molecular Formula: C₁₂H₁₀ClNO
• Molecular Weight: 233.69348
• Mol File: 108082-72-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 342.8°C at 760 mmHg
• Flash Point: 161.1°C
• Appearance: /
• Density: 1.225g/cm³
• Vapor Pressure: 0.000146mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: 2-8°C
• PKA: -0.54±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE(108082-72-0)
• EPA Substance Registry System: 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE(108082-72-0)

Safety Data

• Hazardous Substances Data: 108082-72-0(Hazardous Substances Data)

Usage

General Description

2-Chloro-3-benzyloxymethylpyridine is a chemical compound with the molecular formula C13H11ClNO. It is a pyridine derivative with a chlorine atom and a benzyloxy group attached to the third and second positions of the pyridine ring, respectively. 2-CHLORO-3-BENZYLOXYMETHYLPYRIDINE is commonly used in organic synthesis as a building block for the preparation of various pharmaceutical and agrochemical products. It has been studied for its potential applications in the fields of medicine and agriculture due to its unique chemical properties and reactivity. Additionally, 2-Chloro-3-benzyloxymethylpyridine may also have other industrial and research-related uses, making it a versatile and important chemical in various scientific and technological applications.

InChI:InChI=1/C12H10ClNO/c13-12-11(7-4-8-14-12)15-9-10-5-2-1-3-6-10/h1-8H,9H2

Upstream product

• 6636-78-8 2-chloro-3-hydroxypyridine 
• 100-44-7 benzyl chloride 
• 67-68-5 dimethyl sulfoxide 
• 100-39-0 benzyl bromide 

Downstream Products

• 887593-96-6 3-(benzyloxy)-2-hydrazinylpyridine 
• 109-00-2 3-HYDROXYPYRIDINE 
• 142328-06-1 4-oxo-4,5,6,7-tetrahydro-[2,1,3]benzoxadiazole 
• 123631-83-4 2,3-dimethoxy-4-hydroxypyridine 
• 13472-83-8 2-methoxy-3-hydroxypyridine 
• 1065608-70-9 8-Phenylmethoxy-1,2,4-triazolo[4,3-a]pyridine 
• 156840-59-4 8-chloro-2,3-dihydro-1,4-dioxino<2,3-b>pyridine 
• 156840-58-3 2-(2-hydroxyethoxy)-3-pyridinol 
• 129421-32-5 2,3-dihydro-1,4-dioxino<2,3-b>pyridine 
• 108082-73-1 2-[2-(5-methyl-4-imidazolylmethylthio)ethyl]amino-3-benzyloxypyridine 
• 156840-57-2 1-benzyloxy-2-<3-benzyloxy-2-(pyridinyloxy)>ethane 

Relevant articles and documents

Total synthesis of 4-epi-atpenin A5 as a potent nematode complex II inhibitor

It is clear that atpenins and their analogs are useful chemical tools for elucidation of complex II functionality and that they could act as lead compounds for the development of novel helminth complex II-specific inhibitors. Recently, we discovered 4-epi

TDO2 INHIBITORS

Presently provided are inhibitors of cellularly expressed TDO2 and pharmaceutical compositions thereof, useful for modulating an activity of tryptophan 2, 3 dioxygenase; treating immunosuppression; treating a medical conditions that benefit from the inhibition of tryptophan degradation; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; and treating tumor-specific immunosuppression associated with cancer.

3-`(HETERO) ARYLMETHOXY ! PYRIDINES AND THEIR ANALOGUES AS P38 MAP KINASE INHIBITORS

Compounds of the formula (I), wherein: -X=Y- is selected from -CR2=CR3- and -CR2=N-; R1 is selected from H, halo, NRR', NHC(=O)R, NHC(=O)NRR', NH2SO2R, and C(=O)NRR'; R2 and R3 (where present) are independently selected from H, optionally substituted C1-7 alkyl, optionally substituted C5-20 aryl, optionally substituted C3-20 heterocyclyl, halo, amino, amido, hydroxy, ether, thio, thioether, acylamido, ureido and sulfonamino; R4 is an optionally substituted C5-20 aryl or C5-20 heteroaryl group; and R5 is selected from R5’, halo, NHR5’, C(=O)NHR5’, OR5’, SR5’, NHC(=O)R5’, NHC(=O)NHR5’, NHS(=O)R5’, wherein R5’ is H or C1-3 alkyl (optionally substituted by halo, NH2, OH, SH) are disclosed for use in therapy and for treating diseases ameliorated by inhibiting p38 MAP kinase.