129421-32-5

Basic information

• Product Name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
• Synonyms: 1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-Dioxino[2,3-b];1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI)
• CAS NO: 129421-32-5
• Molecular Formula: C7H7NO2
• Molecular Weight: 137.14
• Product Categories: PYRIDINE;Heterocycle-Pyridine series
• Mol File: 129421-32-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 234°C
• Flash Point: 84°C
• Appearance: /
• Density: 1.229
• Vapor Pressure: 0.1mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.93±0.20(Predicted)
• CAS DataBase Reference: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(129421-32-5)
• EPA Substance Registry System: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(129421-32-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 129421-32-5(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1,4-dioxino[2,3-b]pyridine is a chemical compound categorized under the pyridine and piperidine alkaloids. Pyridine alkaloids can be found in nature and have also been synthesized in laboratory conditions for a variety of applications. Though the chemical does not have significant commercial uses, it is often utilized as a research compound, mainly used in the synthesis of pharmaceutical intermediates due to its reactivity properties. The safety, toxicity, and environmental impact of 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine are not yet fully understood due to limited studies, therefore it is recommended to handle it under professional supervision.

InChI:InChI=1/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2

Upstream product

• 84719-32-4 3-Hydroxy-2(1H)-pyridinone 
• 106-93-4 ethylene dibromide 
• 16867-04-2 dihydroxypyridine 
• 107-04-0 1-Bromo-2-chloroethane 
• 218632-01-0 3-fluoro-4-nitrobenzonitrile 
• 107-21-1 ethylene glycol 
• 156840-57-2 1-benzyloxy-2-<3-benzyloxy-2-(pyridinyloxy)>ethane 
• 108082-72-0 2-chloro-3-benzyloxypyridine 
• 6636-78-8 2-chloro-3-hydroxypyridine 
• 156840-58-3 2-(2-hydroxyethoxy)-3-pyridinol 

Downstream Products

• 95897-49-7 7-Brom-pyrido<2,3-b><1,4>dioxen 
• 643067-83-8 8-bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine 
• 156840-59-4 8-chloro-2,3-dihydro-1,4-dioxino<2,3-b>pyridine 

Relevant articles and documents

AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS

The present invention relates to azabicyclic (thio)amide compounds and the uses thereof for controlling phytopathogenic microorganisms such as phytopathogenic fungi. It also relates to processes and intermediates for preparing these compounds

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).

CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER

[Object] It is to provide a novel LXRβ agonist useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease. [Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate: (wherein, each V and W independently show N or C—R7; each X and Y independently show CH2, C═O, SO2, etc; Z shows CH or N; each R1, R2 and R7 independently show a hydrogen atom, C1-8 alkyl group, etc.; R3 shows C1-8 alkyl group; R4 shows an optionally substituted C6-10 aryl group or an optionally substituted 5- to 11-membered heterocyclic group; R5 and R6 show a hydrogen atom, etc.; L shows a C1-8 alkyl chain optionally substituted with an oxo group, etc.; and n shows any integer of 0 to 2.)