129421-32-5

Basic information

• Product Name: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine
• Synonyms: 1,4-Dioxino[2,3-b]pyridine, 2,3-dihydro;2,3-Dihydro-1,4-dioxino[2,3-b]pyridine;2,3-Dihydro-1,4-Dioxino[2,3-b];1,4-Dioxino[2,3-b]pyridine,2,3-dihydro-(9CI)
• CAS NO: 129421-32-5
• Molecular Formula: C7H7NO2
• Molecular Weight: 137.14
• Product Categories: PYRIDINE;Heterocycle-Pyridine series
• Mol File: 129421-32-5.mol

Chemical Properties

• Boiling Point: 234°C
• Flash Point: 84°C
• Appearance: /
• Density: 1.229
• Vapor Pressure: 0.1mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.93±0.20(Predicted)
• CAS DataBase Reference: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(129421-32-5)
• EPA Substance Registry System: 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine(129421-32-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 129421-32-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine is used as a research compound for the synthesis of pharmaceutical intermediates. Its reactivity properties make it a valuable component in the development of new drugs and medications.
Used in Laboratory Synthesis:
2,3-Dihydro-1,4-dioxino[2,3-b]pyridine is used as a starting material in the synthesis of various chemical compounds. Its unique structure and reactivity properties allow for the creation of a wide range of products in laboratory settings.
Note: Due to the limited studies on the safety, toxicity, and environmental impact of 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine, it is recommended to handle 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine under professional supervision.

InChI:InChI=1/C7H7NO2/c1-2-6-7(8-3-1)10-5-4-9-6/h1-3H,4-5H2

Upstream product

• 84719-32-4 3-Hydroxy-2(1H)-pyridinone 
• 106-93-4 ethylene dibromide 
• 156840-58-3 2-(2-hydroxyethoxy)-3-pyridinol 
• 6636-78-8 2-chloro-3-hydroxypyridine 
• 108082-72-0 2-chloro-3-benzyloxypyridine 
• 156840-57-2 1-benzyloxy-2-<3-benzyloxy-2-(pyridinyloxy)>ethane 
• 16867-04-2 dihydroxypyridine 
• 218632-01-0 3-fluoro-4-nitrobenzonitrile 
• 107-21-1 ethylene glycol 
• 107-04-0 1-Bromo-2-chloroethane 

Downstream Products

• 95897-49-7 7-Brom-pyrido<2,3-b><1,4>dioxen 
• 643067-83-8 8-bromo-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine 
• 156840-59-4 8-chloro-2,3-dihydro-1,4-dioxino<2,3-b>pyridine 

Relevant articles and documents

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CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER

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8-Piperazinyl-2,3-dihydro-1,4-dioxinopyridine Derivatives: Synthesis and Interaction with 5-HT Serotonin Binding Sites

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1,4-Dioxinopyridines and 1,4-Oxathiinopyridines

Reaction of 3-hydroxy-2-pyridones 1 or 3-hydroxy-2-pyridinthiones 2 with sodium hydride and 1,2-dibromoethane in hexamethylphosphorous triamide gives 1,4-dioxinopyridines 3 and 1,4-oxathiinopyridines 4, respectively.Nitration of 3 affords nitro-1,4-dioxinopyridines 5 which can be hydrogenated to amino-1,4-dioxinopyridines 7.