1082746-75-5

Basic information

• Product Name: ethyl 1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxylate
• Synonyms: ethyl 1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxylate
• CAS NO: 1082746-75-5
• Molecular Weight: 361.227
• Mol File: 1082746-75-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxylate(1082746-75-5)
• EPA Substance Registry System: ethyl 1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxylate(1082746-75-5)

Safety Data

• Hazardous Substances Data: 1082746-75-5(Hazardous Substances Data)

Upstream product

• 5814-38-0 ethyl 4-chlorobenzoylpyruvate 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 98-86-2 acetophenone 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 65356-49-2 ethyl 4-(4-chlorophenyl)-2-hydroxy-4-oxobut-2-enoate 

Downstream Products

• 1082746-80-2 N-(1-hexadecyl)-1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxamide 
• 1082746-77-7 N-(1-oleyl)-1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxamide 
• 477712-01-9 1,5-bis(4-chlorophenyl)-1H-pyrazole-3-carboxylic acid 

Relevant articles and documents

Structure–activity relationship studies of 3-substituted pyrazoles as novel allosteric inhibitors of MALT1 protease

We report the discovery of a novel series of 1,5-bisphenylpyrazoles as potent MALT1 inhibitors. Structure–activity relationship exploration of a hit compound led to a potent MALT1 inhibitor. Compound 33 showed strong activity against MALT1 (IC50/sub

Structural study of diarylazoles related to Rimonabant

The structures of three diarylazoles (two pyrazoles and one 1,2,4-triazole) related to Rimonabant have been determined by X-ray crystallography. The conformation of both aryl groups in the new structures is discussed with regard to other related compounds