108574-21-6Relevant articles and documents
A new method for the synthesis of acyl-diazenes using NaNO 2-Ac2O
Li, Jian-Ping,Liu, Ping,Xue, Wan-Xin,Wang, Yu-Lu
, p. 433 - 435 (2003)
An efficient and convenient method for the synthesis of acyl-diazenes from acylhydrazines using NaNO2-acetic anhydride as a novel oxidant agent is reported. The reaction gives excellent yields and the reaction time is not long.
Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase
Tirapegui, Cristian,Acevedo-Fuentes, Williams,Dahech, Pablo,Torrent, Claudia,Barrias, Pablo,Rojas-Poblete, Macarena,Mascayano, Carolina
, p. 1649 - 1653 (2017/04/04)
Two series of diaza derivatives were prepared by solvent-free condensation of benzoic acid and 4-substituted phenylhydrazines in order to obtain phenylhydrazides (HYD series) and, by oxidation of these compounds, the corresponding benzoyldiazenes (DIA series). Both sets were evaluated as inhibitors of soybean 15-lipoxygenase activity and antioxidant capability in the FRAP and CUPRAC assays. The most potent inhibitors of both series exhibited IC50 values in the low micromolar range. Kinetic studies showed that at least the more active compounds were competitive inhibitors. Docking results indicated that the most potent inhibitor interacts strongly with Ile-839 and iron in the active site.
Phase transfer catalysed synthesis of acyldiazenes from acylhydrazines
Niu, Yong-Sheng,Li, Jian-Ping
, p. 551 - 552 (2007/10/03)
A two-phase catalysed dehydrogenation synthesis of acyldiazenes from acylhydrazines using 2,4,6-tri-t-butylphenol/Fe(CN)6 3-/NaOH is reported.