1087606-32-3

Upstream product

• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 106-96-7 propargyl bromide 

Downstream Products

• 1111322-32-7 C₁₂H₁₂O 
• 1126527-59-0 3-(3-chlorophenyl)-1,10-dimethyl-3,11b-dihydro-6H-chromeno[4',3':4,5]pyrano[2,3-c]pyrazole 
• 37391-68-7 2-methyl-6H-chromeno[4,3-b]quinoline 
• 1238518-89-2 C₃₁H₂₄ClN₅O 
• 1262386-18-4 9-methyl-2-phenyl-5H,10bH-pyrano[3,4-c]chromene-1-carbonitrile 
• 1242080-97-2 (E)-5-methyl-2-(2-propynyloxy)benzaldehyde oxime 
• 1383545-90-1 dimethyl 8-methyl-3-phenyl-1,9b-dihydrocyclopenta[c]chromene-2,2(4H)-dicarboxylate 
• 1383545-72-9 dimethyl 2-(5-methyl-2-((3-phenylprop-2-yn-1-yl)oxy)phenyl)cyclopropane-1,1-dicarboxylate 
• 1610629-03-2 N-(2-(3-(4-methoxyphenyl)prop-2-ynyloxy)-5-methylbenzylidene)tert-butylamine 
• 1610629-24-7 (E)-N-tert-butyl-2-(4-methoxystyryl)-5-methylbenzofuran-3-amine 
• 1610629-37-2 C₁₈H₁₆O₃ 
• 1415717-47-3 2-(5-methyl-2-(prop-2-ynyloxy)phenyl)furan 
• 1354780-70-3 11-methyl-14-phenyl-12b,14-dihydro-7H,13H-chromeno[4',3':4,5]pyrano[3,2-c][1,8]naphthyridin-13-one 
• 1279702-73-6 C₁₅H₂₀O₃ 

Relevant academic research and scientific papers

Wittig olefination and thiol mediated 7-endo-trig radical cyclization: novel synthesis of oxepin derivatives

Thiophenol-mediated 7-endo radical cyclization for the synthesis of seven-membered cyclic ethers is described. This method can be successfully applied to synthesize various benzoxepin derivatives, which are present in many natural products as building blo

Nucleophilic addition of amines to ruthenium carbenes: Ortho-(alkynyloxy)benzylamine cyclizations towards 1,3-benzoxazines

A new ruthenium-catalyzed cyclization of ortho-(alkynyloxy)benzylamines to dihydro-1,3-benzoxazines is reported. The cyclization is thought to take place via the vinyl ruthenium carbene intermediates which are easily formed from [CpRuCl(cod)] and N2CHSiMe3. The mild reaction conditions and the efficiency of the procedure allow the easy preparation of a broad range of new 2-vinyl-2-substituted 1,3-benzoxazine derivatives. Rearrangement of an internal C(sp) in the starting material into a tetrasubstituted C(sp3) atom in the final 1,3-benzoxazine is highly remarkable.

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors

A novel series of 35 angularly fused pentacyclic 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridin-5-ium chlorides were designed and synthesized. Their cytotoxic activities were investigated against six human

Catalyst-free regioselective synthesis of benzopyran-annulated thiopyrano[2,3-b]thiochromen-5-(4H)-one derivatives by domino-Knoevenagel-hetero-Diels-Alder reaction of terminal alkynes with 4-hydroxy dithiocoumarin in aqueous medium

The synthesis of novel pentacyclic benzopyran-annulated thiopyrano[2,3-b] thiochromen-5(4H)-ones has been described by domino-Knoevenagel-hetero-Diels-Alder reaction of 4-hydroxy dithiocoumarin and O-propargylated salicylaldehyde in aqueous medium and in

A facile one-pot regioselective synthesis of functionalized novel benzo[f]chromeno[4,3-b][1,7]naphthyridines and benzo[f][1,7]naphthyridines via an imino Diels-Alder reaction

A novel series of functionalized 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and 1,3-diphenylbenzo[f][1,7]naphthyridines have been synthesized by an efficient regioselective one-pot multicomponent synthesis through intra and intermolecular imino Diels-

Catalyst-free domino-Knoevenagel-hetero-Diels-Alder reaction of terminal alkynes in water: an efficient one-step synthesis of indole-annulated thiopyranobenzopyran derivatives

The domino-Knoevenagel-hetero-Diels-Alder reaction of O-propargylated salicylaldehyde and 1-methylindoline-2-thione in aqueous medium in the absence of Lewis acid has been described for the synthesis of hitherto unreported indole-annulated pentacyclic het

An improved synthesis of natural product inspired chromenopyrrolizines and chromenoindolizines scaffolds: Rapid access to the diverse pyrrolizine analogs of aza-medicarpin and tetracyclic isolamellarin core through a general base and metal free strategy

An improved synthesis for easy access to the natural product inspired chromenopyrrolizine and chromenoindolizine scaffolds is delineated. The strategy involves controlled thermal activation of diverse salicylaldehyde tethered dipolarophiles having the str

Highly enantioselective synthesis of chiral 7-ring O- and N-heterocycles by a one-pot nitro-Michael-cyclization tandem reaction

A concise enantioselective approach to synthesise medium-sized 7-ring O- and N-heterocycles has been developed. The synthetic strategy relies on an organocatalytic nitro-Michael-nitrile oxide cycloaddition tandem reaction, leading to the corresponding chiral benzoxe- and benzazepine derivatives containing an additional fused dihydroisoxazoline ring in good yields and excellent enantioselectivities (up to 97% ee).

Zirconium oxide (NP) - Ionic liquid as an efficient media for the domino Knoevenagel hetero Diels-Alder reaction with unactivated alkynes

Immobilized ZrO2-nanopowder (NP) in ionic liquid and different organic solvents was used as a suitable Lewis-acid for the synthesis of polycyclic heterocycles which contains pyran-based skeletons. Reaction of O-propargylated salicylaldehyde wit

Lewis acid-catalyzed intramolecular [3+2] cycloaddition of cyclopropane 1,1-diesters with alkynes for the synthesis of cyclopenta[c]chromene skeletons

An efficient method to construct cyclopenta[c]chromene skeletons by Lewis acid-catalyzed intramolecular [3+2] cycloaddition of cyclopropane 1,1-diesters with alkynes is presented. Two new fused cycles can be formed in one step in moderate to excellent yie