109-82-0Relevant academic research and scientific papers
Synthesis of [3-13C]-, [4-13C]- and [11- 13C]-porphobilinogen
Dawadi, Prativa B. S.,Schulten, Els A. M.,Lugtenburg, Johan
, p. 341 - 349 (2009)
[4-13C]-porphobilinogen 1a, [3-13C]-porphobilinogen 1b and [11-13C]-porphobilinogen 1c are prepared from [1- 13C]-3-(tetrahydropyran-20-yloxy)-propionaldehyde 2a, methyl [4- 13C]-4-nitrobutyrate 3b and [1-13C]-isocyanoacetonitrile 5c, respectively. The building blocks 2, 3 and 5 can be prepared efficiently in any isotopomeric form. Via base-catalyzed condensation of these building blocks porphobilinogen can be enriched with 13C and 15N stable isotopes at any position and combination of positions. Copyright
Chemistry of α-Amino Nitriles. Exploratory Experiments on Thermal Reactions of α-Amino Nitriles
Xiang, Yi-Bin,Drenkard, Susanne,Baumann, Karl,Hickey, Deirdre,Eschenmoser, Albert
, p. 2209 - 2250 (2007/10/02)
The paper extends a previously published report on chemical properties of α-amino nitriles and of members of the C3H4N2 ensemble (Scheme 1) as observed in experiments carried out under non-aqueous conditions.The reactions investigated and the observations made are summarized in some detail in the English footnotes (*) referring to Schemes 1-17 and Fig. 1.
Preparation of Monomeric Methyleneaminoacetonitrile H2C=N-CH2-CN in the Gas Phase
Dammel, Ralph,Bock, Hans
, p. 810 - 814 (2007/10/02)
The reactive intermediate methyleneaminoacetonitrile H2C=N-CH2-CN has been generated via thermal retrotrimerization of N,N',N''-tris(cyanomethyl)hexahydro-s-triazine and characterized by its photoelectron, mass and low-temperature NMR spectra.A fully geometry-optimized MNDO calculation allows to assign the observed ionization energies and yields estimates for other molecular properties, e.g. a rather high dipole moment. - Methyleneaminoacetonitrile Monomer and Trimer, Thermal Retrotrimerization, PE Spectra, MNDO Calculations, 1H NMR Spectra
