1093418-75-7

Basic information

• Product Name: 4-BroMo-2-iodo-benzoic acid Methyl ester
• Synonyms: 4-BroMo-2-iodo-benzoic acid Methyl ester;Methyl 4-bromo-2-iodobenzoate
• CAS NO: 1093418-75-7
• Molecular Formula: C₈H₆BrIO₂
• Molecular Weight: 340.94051
• EINECS: -0
• Mol File: 1093418-75-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: <50℃
• Boiling Point: 326.2±27.0 °C(Predicted)
• Appearance: /
• Density: 2.059±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-BroMo-2-iodo-benzoic acid Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BroMo-2-iodo-benzoic acid Methyl ester(1093418-75-7)
• EPA Substance Registry System: 4-BroMo-2-iodo-benzoic acid Methyl ester(1093418-75-7)

Safety Data

• Hazardous Substances Data: 1093418-75-7(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-iodo-benzoic acid Methyl ester is a type of organic compound, which is characterized by the presence of halogens bromine and iodine, as well as a carboxylic acid ester functional group. Its molecular formula is C8H6BrIO2 and it falls under the category of aryl halides and esters. 4-BroMo-2-iodo-benzoic acid Methyl ester, as an aromatic ester, is likely to be involved in various reactions that form complex organic structures, which are useful in the development of new drugs and various chemical products. Its role may extend to basic academic research as well as industrial chemical applications. As of now, detailed information about its physical properties and safety handling is not widely available and requires further documentation and research.

Upstream product

• 1133123-02-0 4-bromo-2- iodobenzoic acid 
• 74-88-4 methyl iodide 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 67-56-1 methanol 
• 135484-83-2 2-amino-4-bromo-benzoic acid methyl ester 
• 619-42-1 4-methoxycarbonylphenyl bromide 

Downstream Products

• 1223434-15-8 methyl 4-bromo-2-cyanobenzoate 
• 1223434-16-9 4-bromo-2-cyanobenzoic acid 
• 861605-94-9 2-phenoxy-4-bromobenzoic acid 
• 99515-51-2 phenyl 4-bromo-2-hydroxybenzoate 
• 1016313-33-9 C₁₄H₁₁BrO₃ 
• 1261470-87-4 5-bromo-1-iodo-2-benzaldehyde 
• 1261438-69-0 (4-bromo-2-iodophenyl)methanol 
• 1190360-23-6 3‐bromo‐9,9‐dimethyl‐9H‐fluorene 

Relevant articles and documents

Deprotonative cadmation of functionalized aromatics

This communication describes the deproto-metalation of a large range of aromatics including heterocycles using a newly developed lithium-cadmium base; the reaction proceeds at room temperature with an excellent chemoselectivity and efficiency, and proved to be regioselective in most cases. The Royal Society of Chemistry.

CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME

The description relates to cereblon E3 ligase binding compounds, including bifunctional compounds comprising the same, which find utility as modulators of targeted ubiquitination, especially inhibitors of a variety of polypeptides and other proteins which are degraded and/or otherwise inhibited by bifunctional compounds according to the present disclosure. In particular, the description provides compounds, which contain on one end a ligand which binds to the cereblon E3 ubiquitin ligase and on the other end a moiety which binds a target protein such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of that protein. Compounds can be synthesized that exhibit a broad range of pharmacological activities consistent with the degradation/inhibition of targeted polypeptides of nearly any type.

A photoredox-neutral Smiles rearrangement of 2-aryloxybenzoic acids

We report on the use of visible light photoredox catalysis for the radical Smiles rearrangement of 2-aryloxybenzoic acids to obtain aryl salicylates. The method is free of noble metals and operationally simple and the reaction can be run under mild batch or flow conditions. Being a redox neutral process, no stoichiometric oxidants or reductants are needed.