1261470-87-4

Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-2-iodobenzaldehyde is used as an intermediate for the synthesis of various pharmaceutical compounds. Its unique structure with two halogen substituents allows for versatile chemical reactions, making it a valuable building block in the development of new drugs.
Used in Dye Industry:
4-Bromo-2-iodobenzaldehyde is used as a starting material for the production of various dyes. Its halogenated benzene ring structure can be modified through chemical reactions to create a wide range of dyes with different properties and applications.
Used in Agrochemical Industry:
4-Bromo-2-iodobenzaldehyde is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and structural diversity make it a useful component in the development of new and effective agrochemical products.
Used in Organic Chemistry Research:
4-Bromo-2-iodobenzaldehyde is used as a research compound in the field of organic chemistry. Its unique structure and reactivity make it an interesting subject for studying various chemical reactions and transformations, contributing to the advancement of organic chemistry knowledge.

Upstream product

• 106-38-7 para-bromotoluene 
• 260558-15-4 4-bromo-2-iodo-1-methylbenzene 
• 885681-96-9 4-bromo-1-(bromomethyl)-2-iodobenzene 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 135484-83-2 2-amino-4-bromo-benzoic acid methyl ester 
• 1261438-69-0 (4-bromo-2-iodophenyl)methanol 
• 1093418-75-7 methyl 4-bromo-2-iodobenzoate 

Downstream Products

• 1279129-86-0 (Z)-1,2-bis(4-bromo-2-iodophenyl)ethene 
• 689291-90-5 (E)-N-(5-bromo-2-iodobenzylidene)-2-methylpropan-2-amine 
• 1279129-97-3 5-(2,4,6-tri-tert-butylphenyl)dibenzo[b,f]borepin-3,7-dicarboxylic acid 
• 1279129-93-9 3,7-bis(4-methoxyphenyl)-5-(2,4,6-tri-tert-butylphenyl)dibenzo[b,f]borepin 
• 1279129-91-7 3,7-di(thiophen-2-yl)-5-(2,4,6-tri-tert-butylphenyl)dibenzo[b,f]borepin 
• 1279129-88-2 3,7-dibromo-5-(2,4,6-tri-tert-butylphenyl)dibenzo[b,f]borepin 

Relevant academic research and scientific papers

INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE - SYNTHESIS AND USE THEREOF FOR TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND LYMPHOMA

The present invention relates to new compounds of general formula I, their synthesis, their pharmaceutically acceptable salts, and their use in treatment of T-cell acute lymphoblastic leukemia and lymphoma.

Nonplanar Tub-Shaped Benzocyclooctatetraenes via Halogen-Radical Ring Opening of Dihydrobiphenylenes

A novel tandem Ru-catalyzed [2+2+2] cycloaddition of arylenynes to dihydrobiphenylenes followed by halogen-radical ring opening has been developed for the construction of tub-shaped halogenated benzocyclooctatetraenes (bCOT's). Cross-couplings and Diels-Alder reactions of the brominated bCOT's allow the formation of the corresponding eight-membered ring-fused PAH's. The halogen-radical ring opening probably occurs via a selective formation of a bis-allyl radical at the 1,3-cyclohexadiene moiety, halogenation at the bridgehead carbon, and finally electrocyclic ring opening.

Iodolopyrazolium Salts: Synthesis, Derivatizations, and Applications

The synthesis of iodolopyrazolium triflates via an oxidative cyclization of 3-(2-iodophenyl)-1H-pyrazoles is described. The reaction is characterized by a broad substrate scope, and various applications of these novel cyclic iodolium salts acting as useful synthetic intermediates are demonstrated, in particular in site-selective ring openings. This was finally applied to generate derivatives of the anti-inflammatory drug celecoxib. Their application as highly active halogen-bond donors is shown as well.

F- Nucleophilic-Addition-Induced [3 + 2] Annulation: Direct Access to CF3-Substituted Indenes

An efficient [3 + 2] annulation of (2,2-difluorovinyl)-2-iodoarenes and internal alkynes was developed for the synthesis of 1-(trifluoromethyl)-1H-indenes. The success of this strategy hinges upon a well-balanced process for the generation of two transient reactive species, specifically trifluoroethylsilver and alkenylpalladium intermediates, in the same molecule, as well as a smooth transmetalation step, which delicately joins together these two different metallic intermediates.

Functionalized dibenzoborepins as components of small molecule and polymeric π-conjugated electronic materials

We present the synthesis and characterization of dibenzo[b,f]borepins (DBBs) functionalized at the para and meta position with respect to the boron center in order to understand how regiochemical issues influence photophysical and electrochemical properti

Organic halogenation chemistry as a vital tool for the construction of functional π-conjugated materials

Recent and ongoing efforts by the Tovar research group to exploit organic halogenation chemistry for the development of complex organic electronic materials are described. Standard synthetic approaches involving free-radical and electrophilic reaction pathways are presented along with strategies that use ionizable protons or triazenes as masking groups for aromatic halides. Forward synthetic processes that highlight the extended chemistry that can be applied to these halogenated substrates to give complex π-conjugated molecules are also discussed. The examples presented are specific to work from the groups laboratories, but the halogenation procedures are sufficiently general to be suitable for use on many other conjugated frameworks. Georg Thieme Verlag Stuttgart New York.

BORON-CONTAINING PI-ELECTRON MATERIALS INCORPORATING FORMALLY AROMATIC AND NEUTRAL BOREPIN RINGS

The synthesis, functionalization and characterization of borepin-based extended pi-electron molecules is disclosed. Bulky substituents shielded the vacant boron p-orbitals thus allowing synthetic manipulation and purification under ambient lab conditions.