110249-21-3

Basic information

• Product Name: 4-(benzyloxy)-2-methylquinazoline
• Synonyms: 4-(benzyloxy)-2-methylquinazoline
• CAS NO: 110249-21-3
• Molecular Formula: C₁₆H₁₄N₂O
• Molecular Weight: 250.29516
• Mol File: 110249-21-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(benzyloxy)-2-methylquinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2-methylquinazoline(110249-21-3)
• EPA Substance Registry System: 4-(benzyloxy)-2-methylquinazoline(110249-21-3)

Safety Data

• Hazardous Substances Data: 110249-21-3(Hazardous Substances Data)

Upstream product

• 25116-00-1 2-acetamidobenzonitrile 
• 118-92-3 anthranilic acid 
• 100-39-0 benzyl bromide 
• 1769-24-0 4-hydroxy-2-methylquinazoline 

Relevant articles and documents

DABCO-catalyzed one-pot three component synthesis of dihydropyrano[3,2-c]chromene substituted quinazolines and their evaluation towards anticancer activity

A facile DABCO promoted one-pot three component synthesis of a new series of C–C linked bis-heterocycle containing dihydropyrano[c]chromene as highly fused oxa-heteryl group at C-2 position of quinazoline was developed. Quinazoline-2-carbaldehyde, substituted 4-hydroxycoumarin and ethyl cyanoacetate were used as key components in the Knoevenagel–Michael addition reaction to get the titled compounds. These compounds were screened for anti-cancer activity against the breast cancer cell lines of MDA-MB 231, and MDA-MB 453.